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327 results

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Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CG, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV. Xiang Y, et al. Among authors: dang cv. J Clin Invest. 2015 Jun;125(6):2293-306. doi: 10.1172/JCI75836. Epub 2015 Apr 27. J Clin Invest. 2015. PMID: 25915584 Free PMC article.
Q-ing tumor glutaminase for therapy.
Stine ZE, Dang CV. Stine ZE, et al. Among authors: dang cv. Oncotarget. 2015 Nov 17;6(36):38440-1. doi: 10.18632/oncotarget.6301. Oncotarget. 2015. PMID: 26564960 Free PMC article. No abstract available.
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.
Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, Dang CV, Riggins GJ. Seltzer MJ, et al. Among authors: dang cv. Cancer Res. 2010 Nov 15;70(22):8981-7. doi: 10.1158/0008-5472.CAN-10-1666. Epub 2010 Nov 2. Cancer Res. 2010. PMID: 21045145 Free PMC article.
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.
Shukla K, Ferraris DV, Thomas AG, Stathis M, Duvall B, Delahanty G, Alt J, Rais R, Rojas C, Gao P, Xiang Y, Dang CV, Slusher BS, Tsukamoto T. Shukla K, et al. Among authors: dang cv. J Med Chem. 2012 Dec 13;55(23):10551-63. doi: 10.1021/jm301191p. Epub 2012 Nov 30. J Med Chem. 2012. PMID: 23151085 Free PMC article.
MYC and metabolism on the path to cancer.
Hsieh AL, Walton ZE, Altman BJ, Stine ZE, Dang CV. Hsieh AL, et al. Among authors: dang cv. Semin Cell Dev Biol. 2015 Jul;43:11-21. doi: 10.1016/j.semcdb.2015.08.003. Epub 2015 Aug 12. Semin Cell Dev Biol. 2015. PMID: 26277543 Free PMC article. Review.
MYC, Metabolism, and Cancer.
Stine ZE, Walton ZE, Altman BJ, Hsieh AL, Dang CV. Stine ZE, et al. Among authors: dang cv. Cancer Discov. 2015 Oct;5(10):1024-39. doi: 10.1158/2159-8290.CD-15-0507. Epub 2015 Sep 17. Cancer Discov. 2015. PMID: 26382145 Free PMC article. Review.
Splicing and Dicing MYC-Mediated Synthetic Lethality.
Stine ZE, Dang CV. Stine ZE, et al. Among authors: dang cv. Cancer Cell. 2015 Oct 12;28(4):405-406. doi: 10.1016/j.ccell.2015.09.016. Cancer Cell. 2015. PMID: 26461086 Free article.
MYC, Metabolic Synthetic Lethality, and Cancer.
Hsieh AL, Dang CV. Hsieh AL, et al. Among authors: dang cv. Recent Results Cancer Res. 2016;207:73-91. doi: 10.1007/978-3-319-42118-6_4. Recent Results Cancer Res. 2016. PMID: 27557535 Review.
The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth.
Gouw AM, Margulis K, Liu NS, Raman SJ, Mancuso A, Toal GG, Tong L, Mosley A, Hsieh AL, Sullivan DK, Stine ZE, Altman BJ, Schulze A, Dang CV, Zare RN, Felsher DW. Gouw AM, et al. Among authors: dang cv. Cell Metab. 2019 Sep 3;30(3):556-572.e5. doi: 10.1016/j.cmet.2019.07.012. Epub 2019 Aug 22. Cell Metab. 2019. PMID: 31447321 Free PMC article.
327 results