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Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle.
Caputi L, Franke J, Farrow SC, Chung K, Payne RME, Nguyen TD, Dang TT, Soares Teto Carqueijeiro I, Koudounas K, Dugé de Bernonville T, Ameyaw B, Jones DM, Vieira IJC, Courdavault V, O'Connor SE. Caputi L, et al. Among authors: dang tt. Science. 2018 Jun 15;360(6394):1235-1239. doi: 10.1126/science.aat4100. Epub 2018 May 3. Science. 2018. PMID: 29724909
Two Tabersonine 6,7-Epoxidases Initiate Lochnericine-Derived Alkaloid Biosynthesis in Catharanthus roseus.
Carqueijeiro I, Brown S, Chung K, Dang TT, Walia M, Besseau S, Dugé de Bernonville T, Oudin A, Lanoue A, Billet K, Munsch T, Koudounas K, Melin C, Godon C, Razafimandimby B, de Craene JO, Glévarec G, Marc J, Giglioli-Guivarc'h N, Clastre M, St-Pierre B, Papon N, Andrade RB, O'Connor SE, Courdavault V. Carqueijeiro I, et al. Among authors: dang tt. Plant Physiol. 2018 Aug;177(4):1473-1486. doi: 10.1104/pp.18.00549. Epub 2018 Jun 22. Plant Physiol. 2018. PMID: 29934299 Free PMC article.
A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids.
Carqueijeiro I, Dugé de Bernonville T, Lanoue A, Dang TT, Teijaro CN, Paetz C, Billet K, Mosquera A, Oudin A, Besseau S, Papon N, Glévarec G, Atehortùa L, Clastre M, Giglioli-Guivarc'h N, Schneider B, St-Pierre B, Andrade RB, O'Connor SE, Courdavault V. Carqueijeiro I, et al. Among authors: dang tt. Plant J. 2018 May;94(3):469-484. doi: 10.1111/tpj.13868. Epub 2018 Mar 27. Plant J. 2018. PMID: 29438577
Noscapine comes of age.
Chen X, Dang TT, Facchini PJ. Chen X, et al. Among authors: dang tt. Phytochemistry. 2015 Mar;111:7-13. doi: 10.1016/j.phytochem.2014.09.008. Epub 2015 Jan 9. Phytochemistry. 2015. PMID: 25583437 Review.
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