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The controversial world of sirtuins.
Dang W. Dang W. Drug Discov Today Technol. 2014 Jun;12:e9-e17. doi: 10.1016/j.ddtec.2012.08.003. Drug Discov Today Technol. 2014. PMID: 25027380 Free PMC article. Review.
Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.
Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL. Dang W, et al. Cell Metab. 2014 Jun 3;19(6):952-66. doi: 10.1016/j.cmet.2014.04.004. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814484 Free PMC article.
H3K36 methylation promotes longevity by enhancing transcriptional fidelity.
Sen P, Dang W, Donahue G, Dai J, Dorsey J, Cao X, Liu W, Cao K, Perry R, Lee JY, Wasko BM, Carr DT, He C, Robison B, Wagner J, Gregory BD, Kaeberlein M, Kennedy BK, Boeke JD, Berger SL. Sen P, et al. Among authors: dang w. Genes Dev. 2015 Jul 1;29(13):1362-76. doi: 10.1101/gad.263707.115. Genes Dev. 2015. PMID: 26159996 Free PMC article.
Histone H4 lysine 16 acetylation regulates cellular lifespan.
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Dang W, et al. Nature. 2009 Jun 11;459(7248):802-7. doi: 10.1038/nature08085. Nature. 2009. PMID: 19516333 Free PMC article.
543 results