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Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence.
Norsigian CJ, Danhof HA, Brand CK, Oezguen N, Midani FS, Palsson BO, Savidge TC, Britton RA, Spinler JK, Monk JM. Norsigian CJ, et al. Among authors: danhof ha. NPJ Syst Biol Appl. 2020 Oct 20;6(1):31. doi: 10.1038/s41540-020-00151-9. NPJ Syst Biol Appl. 2020. PMID: 33082337 Free PMC article.
Human intestinal enteroids as a model of Clostridioides difficile-induced enteritis.
Engevik MA, Danhof HA, Chang-Graham AL, Spinler JK, Engevik KA, Herrmann B, Endres BT, Garey KW, Hyser JM, Britton RA, Versalovic J. Engevik MA, et al. Among authors: danhof ha. Am J Physiol Gastrointest Liver Physiol. 2020 May 1;318(5):G870-G888. doi: 10.1152/ajpgi.00045.2020. Epub 2020 Mar 30. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32223302 Free PMC article.
Enhancing responsiveness of human jejunal enteroids to host and microbial stimuli.
Ruan W, Engevik MA, Chang-Graham AL, Danhof HA, Goodwin A, Engevik KA, Shi Z, Hall A, Rienzi SCD, Venable S, Britton RA, Hyser J, Versalovic J. Ruan W, et al. Among authors: danhof ha. J Physiol. 2020 Aug;598(15):3085-3105. doi: 10.1113/JP279423. Epub 2020 Jun 13. J Physiol. 2020. PMID: 32428244 Free PMC article.
Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut-Brain Axis.
Engevik MA, Luck B, Visuthranukul C, Ihekweazu FD, Engevik AC, Shi Z, Danhof HA, Chang-Graham AL, Hall A, Endres BT, Haidacher SJ, Horvath TD, Haag AM, Devaraj S, Garey KW, Britton RA, Hyser JM, Shroyer NF, Versalovic J. Engevik MA, et al. Among authors: danhof ha. Cell Mol Gastroenterol Hepatol. 2021;11(1):221-248. doi: 10.1016/j.jcmgh.2020.08.002. Epub 2020 Aug 12. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32795610 Free PMC article.
Rotavirus induces intercellular calcium waves through ADP signaling.
Chang-Graham AL, Perry JL, Engevik MA, Engevik KA, Scribano FJ, Gebert JT, Danhof HA, Nelson JC, Kellen JS, Strtak AC, Sastri NP, Estes MK, Britton RA, Versalovic J, Hyser JM. Chang-Graham AL, et al. Among authors: danhof ha. Science. 2020 Nov 20;370(6519):eabc3621. doi: 10.1126/science.abc3621. Science. 2020. PMID: 33214249 Free PMC article.
Fusobacteriumnucleatum Adheres to Clostridioides difficile via the RadD Adhesin to Enhance Biofilm Formation in Intestinal Mucus.
Engevik MA, Danhof HA, Auchtung J, Endres BT, Ruan W, Bassères E, Engevik AC, Wu Q, Nicholson M, Luna RA, Garey KW, Crawford SE, Estes MK, Lux R, Yacyshyn MB, Yacyshyn B, Savidge T, Britton RA, Versalovic J. Engevik MA, et al. Among authors: danhof ha. Gastroenterology. 2021 Mar;160(4):1301-1314.e8. doi: 10.1053/j.gastro.2020.11.034. Epub 2020 Nov 21. Gastroenterology. 2021. PMID: 33227279 Free PMC article.
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