Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

405 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
Lindskog C, Korsgren O, Pontén F, Eriksson JW, Johansson L, Danielsson A. Lindskog C, et al. J Proteomics. 2012 May 17;75(9):2611-20. doi: 10.1016/j.jprot.2012.03.008. Epub 2012 Mar 21. J Proteomics. 2012. PMID: 22465717
By antibody-based proteomics, we have identified and explored a set of islet cell-specific proteins. A search algorithm in the Human Protein Atlas was set up for identification of islet-specific proteins that yielded 27 hits, of which twelve showed a clear me …
By antibody-based proteomics, we have identified and explored a set of islet cell-specific proteins. A search algorithm in the …
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
Danielsson A, Pontén F, Fagerberg L, Hallström BM, Schwenk JM, Uhlén M, Korsgren O, Lindskog C. Danielsson A, et al. PLoS One. 2014 Dec 29;9(12):e115421. doi: 10.1371/journal.pone.0115421. eCollection 2014. PLoS One. 2014. PMID: 25546435 Free PMC article.
Analysis of whole pancreas identified 146 genes with elevated expression levels, of which 47 revealed a particular higher expression as compared to the other analyzed tissue types, thus termed pancreas enriched. ...In summary, we provide a global analysis of the pan …
Analysis of whole pancreas identified 146 genes with elevated expression levels, of which 47 revealed a particular higher expression …
The transcriptomic and proteomic landscapes of bone marrow and secondary lymphoid tissues.
Andersson S, Nilsson K, Fagerberg L, Hallström BM, Sundström C, Danielsson A, Edlund K, Uhlen M, Asplund A. Andersson S, et al. PLoS One. 2014 Dec 26;9(12):e115911. doi: 10.1371/journal.pone.0115911. eCollection 2014. PLoS One. 2014. PMID: 25541736 Free PMC article.
The Human Protein Atlas project aims to systematically map the human gene and protein expression landscape in a multitude of normal healthy tissues as well as cancers, enabling the characterization of both housekeeping genes and genes that display a tissue-specific …
The Human Protein Atlas project aims to systematically map the human gene and protein expression landscape in a multitude of normal h …
Expression of human leukocyte antigen class I in endocrine and exocrine pancreatic tissue at onset of type 1 diabetes.
Skog O, Korsgren S, Wiberg A, Danielsson A, Edwin B, Buanes T, Krogvold L, Korsgren O, Dahl-Jørgensen K. Skog O, et al. Am J Pathol. 2015 Jan;185(1):129-38. doi: 10.1016/j.ajpath.2014.09.004. Am J Pathol. 2015. PMID: 25524212
In conclusion, a discrepancy in HLA class I expression in islets assessed by IHC was observed compared with that using quantitative techniques showing similar expression of HLA class I in islets and exocrine tissue in subjects with recent-onset type 1 diabetes, nor could a …
In conclusion, a discrepancy in HLA class I expression in islets assessed by IHC was observed compared with that using quantitative t …
Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.
Edqvist PH, Fagerberg L, Hallström BM, Danielsson A, Edlund K, Uhlén M, Pontén F. Edqvist PH, et al. J Histochem Cytochem. 2015 Feb;63(2):129-41. doi: 10.1369/0022155414562646. Epub 2014 Nov 19. J Histochem Cytochem. 2015. PMID: 25411189 Free PMC article.
We have combined a genome-wide transcriptomics analysis, using deep sequencing of mRNA from skin biopsies, with immunohistochemistry-based protein profiling to characterize the landscape of gene and protein expression in normal human skin. ...In conclusion, we have applied …
We have combined a genome-wide transcriptomics analysis, using deep sequencing of mRNA from skin biopsies, with immunohistochemistry- …
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics.
Fagerberg L, Hallström BM, Oksvold P, Kampf C, Djureinovic D, Odeberg J, Habuka M, Tahmasebpoor S, Danielsson A, Edlund K, Asplund A, Sjöstedt E, Lundberg E, Szigyarto CA, Skogs M, Takanen JO, Berling H, Tegel H, Mulder J, Nilsson P, Schwenk JM, Lindskog C, Danielsson F, Mardinoglu A, Sivertsson A, von Feilitzen K, Forsberg M, Zwahlen M, Olsson I, Navani S, Huss M, Nielsen J, Ponten F, Uhlén M. Fagerberg L, et al. Mol Cell Proteomics. 2014 Feb;13(2):397-406. doi: 10.1074/mcp.M113.035600. Epub 2013 Dec 5. Mol Cell Proteomics. 2014. PMID: 24309898 Free PMC article.
Here, we used a quantitative transcriptomics analysis (RNA-Seq) to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody-based profiling of the same tissues. ...The …
Here, we used a quantitative transcriptomics analysis (RNA-Seq) to classify the tissue-specific expression of genes across a r …
Defining the human gallbladder proteome by transcriptomics and affinity proteomics.
Kampf C, Mardinoglu A, Fagerberg L, Hallström BM, Danielsson A, Nielsen J, Pontén F, Uhlen M. Kampf C, et al. Proteomics. 2014 Nov;14(21-22):2498-507. doi: 10.1002/pmic.201400201. Epub 2014 Oct 9. Proteomics. 2014. PMID: 25175928
Here, we employed a genome-wide deep RNA sequencing analysis in 28 human tissues to identify the genes overrepresented in the gallbladder and complemented it with antibody-based immunohistochemistry in 48 human tissues. ...
Here, we employed a genome-wide deep RNA sequencing analysis in 28 human tissues to identify the genes overrepresented in the gallbla …
GPR44 is a pancreatic protein restricted to the human beta cell.
Hellström-Lindahl E, Danielsson A, Ponten F, Czernichow P, Korsgren O, Johansson L, Eriksson O. Hellström-Lindahl E, et al. Acta Diabetol. 2016 Jun;53(3):413-21. doi: 10.1007/s00592-015-0811-3. Epub 2015 Oct 14. Acta Diabetol. 2016. PMID: 26467464
Here, we assess the potential of GPR44 as a surrogate marker for beta cells, in a direct comparison with clinically used biomarker VMAT2. ...CONCLUSION: GPR44 is a highly beta cell-specific target, which potentially offers improved imaging contrast between th …
Here, we assess the potential of GPR44 as a surrogate marker for beta cells, in a direct comparison with clinically used bioma …
The HDAC inhibitor FK228 enhances adenoviral transgene expression by a transduction-independent mechanism but does not increase adenovirus replication.
Danielsson A, Dzojic H, Rashkova V, Cheng WS, Essand M. Danielsson A, et al. PLoS One. 2011 Feb 17;6(2):e14700. doi: 10.1371/journal.pone.0014700. PLoS One. 2011. PMID: 21379379 Free PMC article.
FK228 had positive effects both on Ad5 and Ad5/f35 vectors with a variety of transgenes and promoters, indicating that FK228 works mainly by increasing transgene expression at the transcriptional level. ...This is probably a consequence of alteration of the adenocar …
FK228 had positive effects both on Ad5 and Ad5/f35 vectors with a variety of transgenes and promoters, indicating that FK228 works ma …
Clinical adenoviral gene therapy for prostate cancer.
Schenk E, Essand M, Bangma CH; GIANT FP6 Consortium, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Danielsson A, Dautzenberg IJ, Dzojic H, Erbacher P, Fisher K, Frazier A, Georgopoulos LJ, Hoeben R, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Lindholm L, Magnusson M, Maitland N, Neuberg P, Nilsson B, Ogris M, Remy JS, Scaife M, Schooten E, Seymour L, Totterman T, Uil TG, Ulbrich K, Veldhoven-Zweistra JL, de Vrij J, van Weerden W, Wagner E, Willemsen R. Schenk E, et al. Hum Gene Ther. 2010 Jul;21(7):807-13. doi: 10.1089/hum.2009.206. Hum Gene Ther. 2010. PMID: 20001452 Review.
However, a substantial number of patients experience a recurrence, resulting in spreading of tumor cells to other parts of the body. ...Gene therapy is now being explored in the clinic as a treatment option for the various stages of prostate cancer. Current c …
However, a substantial number of patients experience a recurrence, resulting in spreading of tumor cells to other parts of the …
405 results
Jump to page
Feedback