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Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF).
Cunha DA, Cito M, Grieco FA, Cosentino C, Danilova T, Ladrière L, Lindahl M, Domanskyi A, Bugliani M, Marchetti P, Eizirik DL, Cnop M. Cunha DA, et al. Among authors: danilova t. J Biol Chem. 2017 Sep 8;292(36):14977-14988. doi: 10.1074/jbc.M116.769877. Epub 2017 Jul 11. J Biol Chem. 2017. PMID: 28698383 Free PMC article.
MANF is indispensable for the proliferation and survival of pancreatic β cells.
Lindahl M, Danilova T, Palm E, Lindholm P, Võikar V, Hakonen E, Ustinov J, Andressoo JO, Harvey BK, Otonkoski T, Rossi J, Saarma M. Lindahl M, et al. Among authors: danilova t. Cell Rep. 2014 Apr 24;7(2):366-375. doi: 10.1016/j.celrep.2014.03.023. Epub 2014 Apr 13. Cell Rep. 2014. PMID: 24726366 Free PMC article.
MANF protects human pancreatic beta cells against stress-induced cell death.
Hakonen E, Chandra V, Fogarty CL, Yu NY, Ustinov J, Katayama S, Galli E, Danilova T, Lindholm P, Vartiainen A, Einarsdottir E, Krjutškov K, Kere J, Saarma M, Lindahl M, Otonkoski T. Hakonen E, et al. Among authors: danilova t. Diabetologia. 2018 Oct;61(10):2202-2214. doi: 10.1007/s00125-018-4687-y. Epub 2018 Jul 21. Diabetologia. 2018. PMID: 30032427 Free PMC article.
Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice.
Porokuokka LL, Virtanen HT, Lindén J, Sidorova Y, Danilova T, Lindahl M, Saarma M, Andressoo JO. Porokuokka LL, et al. Among authors: danilova t. Cell Mol Gastroenterol Hepatol. 2019;7(3):655-678. doi: 10.1016/j.jcmgh.2018.12.007. Epub 2018 Dec 27. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30594740 Free PMC article.
259 results