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Validating Stat3 in cancer therapy.
Darnell JE. Darnell JE. Nat Med. 2005 Jun;11(6):595-6. doi: 10.1038/nm0605-595. Nat Med. 2005. PMID: 15937466 No abstract available.
Reduced STAT3 activity in mice mimics clinical disease syndromes.
Shen Y, La Perle KM, Levy DE, Darnell JE Jr. Shen Y, et al. Biochem Biophys Res Commun. 2005 Apr 29;330(1):305-9. doi: 10.1016/j.bbrc.2005.02.154. Biochem Biophys Res Commun. 2005. PMID: 15781265
Transcription factors as targets for cancer therapy.
Darnell JE Jr. Darnell JE Jr. Nat Rev Cancer. 2002 Oct;2(10):740-9. doi: 10.1038/nrc906. Nat Rev Cancer. 2002. PMID: 12360277 Review.
Potential roles of Stat1 and Stat3 in cellular transformation.
Bromberg JF, Darnell JE Jr. Bromberg JF, et al. Cold Spring Harb Symp Quant Biol. 1999;64:425-8. doi: 10.1101/sqb.1999.64.425. Cold Spring Harb Symp Quant Biol. 1999. PMID: 11232317 Review. No abstract available.
Stat3 as an oncogene.
Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C, Darnell JE Jr. Bromberg JF, et al. Cell. 1999 Aug 6;98(3):295-303. doi: 10.1016/s0092-8674(00)81959-5. Cell. 1999. PMID: 10458605
A transcriptional hierarchy involved in mammalian cell-type specification.
Kuo CJ, Conley PB, Chen L, Sladek FM, Darnell JE Jr, Crabtree GR. Kuo CJ, et al. Nature. 1992 Jan 30;355(6359):457-61. doi: 10.1038/355457a0. Nature. 1992. PMID: 1734282
Independent and cooperative activation of chromosomal c-fos promoter by STAT3.
Yang E, Lerner L, Besser D, Darnell JE Jr. Yang E, et al. J Biol Chem. 2003 May 2;278(18):15794-9. doi: 10.1074/jbc.M213073200. Epub 2003 Feb 24. J Biol Chem. 2003. PMID: 12600988
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