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The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells.
Dartois V. Dartois V. Nat Rev Microbiol. 2014 Mar;12(3):159-67. doi: 10.1038/nrmicro3200. Epub 2014 Feb 3. Nat Rev Microbiol. 2014. PMID: 24487820 Free PMC article. Review.
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.
Barry CE 3rd, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn J, Schnappinger D, Wilkinson RJ, Young D. Barry CE 3rd, et al. Among authors: dartois v. Nat Rev Microbiol. 2009 Dec;7(12):845-55. doi: 10.1038/nrmicro2236. Epub 2009 Oct 26. Nat Rev Microbiol. 2009. PMID: 19855401 Free PMC article. Review.
Clinical pharmacology and lesion penetrating properties of second- and third-line antituberculous agents used in the management of multidrug-resistant (MDR) and extensively-drug resistant (XDR) tuberculosis.
Dartois V, Barry CE. Dartois V, et al. Curr Clin Pharmacol. 2010 May;5(2):96-114. doi: 10.2174/157488410791110797. Curr Clin Pharmacol. 2010. PMID: 20156156 Free PMC article. Review.
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy.
Pethe K, Sequeira PC, Agarwalla S, Rhee K, Kuhen K, Phong WY, Patel V, Beer D, Walker JR, Duraiswamy J, Jiricek J, Keller TH, Chatterjee A, Tan MP, Ujjini M, Rao SP, Camacho L, Bifani P, Mak PA, Ma I, Barnes SW, Chen Z, Plouffe D, Thayalan P, Ng SH, Au M, Lee BH, Tan BH, Ravindran S, Nanjundappa M, Lin X, Goh A, Lakshminarayana SB, Shoen C, Cynamon M, Kreiswirth B, Dartois V, Peters EC, Glynne R, Brenner S, Dick T. Pethe K, et al. Among authors: dartois v. Nat Commun. 2010 Aug 24;1(5):57. doi: 10.1038/ncomms1060. Nat Commun. 2010. PMID: 20975714 Free PMC article.
T cell monitoring of chemotherapy in experimental rat tuberculosis.
Foo DG, Tay HC, Siew JY, Singhal A, Camacho L, Bifani P, Dartois V, Hervé M. Foo DG, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2011 Aug;55(8):3677-83. doi: 10.1128/AAC.00136-11. Epub 2011 May 31. Antimicrob Agents Chemother. 2011. PMID: 21628535 Free PMC article.
Mycobacterium tuberculosis infection induces hypoxic lung lesions in the rat.
Heng Y, Seah PG, Siew JY, Tay HC, Singhal A, Mathys V, Kiass M, Bifani P, Dartois V, Hervé M. Heng Y, et al. Among authors: dartois v. Tuberculosis (Edinb). 2011 Jul;91(4):339-41. doi: 10.1016/ Epub 2011 Jun 1. Tuberculosis (Edinb). 2011. PMID: 21636324
Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs.
Subbian S, Tsenova L, O'Brien P, Yang G, Koo MS, Peixoto B, Fallows D, Dartois V, Muller G, Kaplan G. Subbian S, et al. Among authors: dartois v. PLoS Pathog. 2011 Sep;7(9):e1002262. doi: 10.1371/journal.ppat.1002262. Epub 2011 Sep 15. PLoS Pathog. 2011. PMID: 21949656 Free PMC article.
Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions.
Kjellsson MC, Via LE, Goh A, Weiner D, Low KM, Kern S, Pillai G, Barry CE 3rd, Dartois V. Kjellsson MC, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2012 Jan;56(1):446-57. doi: 10.1128/AAC.05208-11. Epub 2011 Oct 10. Antimicrob Agents Chemother. 2012. PMID: 21986820 Free PMC article.
Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis.
Franzblau SG, DeGroote MA, Cho SH, Andries K, Nuermberger E, Orme IM, Mdluli K, Angulo-Barturen I, Dick T, Dartois V, Lenaerts AJ. Franzblau SG, et al. Among authors: dartois v. Tuberculosis (Edinb). 2012 Nov;92(6):453-88. doi: 10.1016/ Epub 2012 Aug 30. Tuberculosis (Edinb). 2012. PMID: 22940006 Review.
Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis.
Carroll MW, Jeon D, Mountz JM, Lee JD, Jeong YJ, Zia N, Lee M, Lee J, Via LE, Lee S, Eum SY, Lee SJ, Goldfeder LC, Cai Y, Jin B, Kim Y, Oh T, Chen RY, Dodd LE, Gu W, Dartois V, Park SK, Kim CT, Barry CE 3rd, Cho SN. Carroll MW, et al. Among authors: dartois v. Antimicrob Agents Chemother. 2013 Aug;57(8):3903-9. doi: 10.1128/AAC.00753-13. Epub 2013 Jun 3. Antimicrob Agents Chemother. 2013. PMID: 23733467 Free PMC article. Clinical Trial.
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