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Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma.
Glas M, Coch C, Trageser D, Dassler J, Simon M, Koch P, Mertens J, Quandel T, Gorris R, Reinartz R, Wieland A, Von Lehe M, Pusch A, Roy K, Schlee M, Neumann H, Fimmers R, Herrlinger U, Brüstle O, Hartmann G, Besch R, Scheffler B. Glas M, et al. Among authors: dassler j. Stem Cells. 2013 Jun;31(6):1064-74. doi: 10.1002/stem.1350. Stem Cells. 2013. PMID: 23390110
Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells.
Kübler K, tho Pesch C, Gehrke N, Riemann S, Dassler J, Coch C, Landsberg J, Wimmenauer V, Pölcher M, Rudlowski C, Tüting T, Kuhn W, Hartmann G, Barchet W. Kübler K, et al. Among authors: dassler j. Eur J Immunol. 2011 Oct;41(10):3028-39. doi: 10.1002/eji.201141555. Epub 2011 Aug 30. Eur J Immunol. 2011. PMID: 21728171 Free article.
Exosomes as nucleic acid nanocarriers.
van den Boorn JG, Dassler J, Coch C, Schlee M, Hartmann G. van den Boorn JG, et al. Among authors: dassler j. Adv Drug Deliv Rev. 2013 Mar;65(3):331-5. doi: 10.1016/j.addr.2012.06.011. Epub 2012 Jun 28. Adv Drug Deliv Rev. 2013. PMID: 22750807 Review.
CD74-NRG1 fusions in lung adenocarcinoma.
Fernandez-Cuesta L, Plenker D, Osada H, Sun R, Menon R, Leenders F, Ortiz-Cuaran S, Peifer M, Bos M, Daßler J, Malchers F, Schöttle J, Vogel W, Dahmen I, Koker M, Ullrich RT, Wright GM, Russell PA, Wainer Z, Solomon B, Brambilla E, Nagy-Mignotte H, Moro-Sibilot D, Brambilla CG, Lantuejoul S, Altmüller J, Becker C, Nürnberg P, Heuckmann JM, Stoelben E, Petersen I, Clement JH, Sänger J, Muscarella LA, la Torre A, Fazio VM, Lahortiga I, Perera T, Ogata S, Parade M, Brehmer D, Vingron M, Heukamp LC, Buettner R, Zander T, Wolf J, Perner S, Ansén S, Haas SA, Yatabe Y, Thomas RK. Fernandez-Cuesta L, et al. Among authors: dassler j. Cancer Discov. 2014 Apr;4(4):415-22. doi: 10.1158/2159-8290.CD-13-0633. Epub 2014 Jan 27. Cancer Discov. 2014. PMID: 24469108