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Page 1
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JLY, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J. Marcotte R, et al. Among authors: datti a. Cancer Discov. 2012 Feb;2(2):172-189. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29. Cancer Discov. 2012. PMID: 22585861 Free PMC article.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.
Vizeacoumar FJ, Arnold R, Vizeacoumar FS, Chandrashekhar M, Buzina A, Young JT, Kwan JH, Sayad A, Mero P, Lawo S, Tanaka H, Brown KR, Baryshnikova A, Mak AB, Fedyshyn Y, Wang Y, Brito GC, Kasimer D, Makhnevych T, Ketela T, Datti A, Babu M, Emili A, Pelletier L, Wrana J, Wainberg Z, Kim PM, Rottapel R, O'Brien CA, Andrews B, Boone C, Moffat J. Vizeacoumar FJ, et al. Among authors: datti a. Mol Syst Biol. 2013 Oct 8;9:696. doi: 10.1038/msb.2013.54. Mol Syst Biol. 2013. PMID: 24104479 Free PMC article.
Inhibition of SREBP1 sensitizes cells to death ligands.
Eberhard Y, Gronda M, Hurren R, Datti A, MacLean N, Ketela T, Moffat J, Wrana JL, Schimmer AD. Eberhard Y, et al. Among authors: datti a. Oncotarget. 2011 Mar;2(3):186-96. doi: 10.18632/oncotarget.239. Oncotarget. 2011. PMID: 21406729 Free PMC article.
Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation.
Simpson CD, Mawji IA, Anyiwe K, Williams MA, Wang X, Venugopal AL, Gronda M, Hurren R, Cheng S, Serra S, Beheshti Zavareh R, Datti A, Wrana JL, Ezzat S, Schimmer AD. Simpson CD, et al. Among authors: datti a. Cancer Res. 2009 Apr 1;69(7):2739-47. doi: 10.1158/0008-5472.CAN-08-2530. Epub 2009 Mar 17. Cancer Res. 2009. PMID: 19293189
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD. Skrtić M, et al. Among authors: datti a. Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015. Cancer Cell. 2011. PMID: 22094260 Free PMC article.
Systematic exploration of essential yeast gene function with temperature-sensitive mutants.
Li Z, Vizeacoumar FJ, Bahr S, Li J, Warringer J, Vizeacoumar FS, Min R, Vandersluis B, Bellay J, Devit M, Fleming JA, Stephens A, Haase J, Lin ZY, Baryshnikova A, Lu H, Yan Z, Jin K, Barker S, Datti A, Giaever G, Nislow C, Bulawa C, Myers CL, Costanzo M, Gingras AC, Zhang Z, Blomberg A, Bloom K, Andrews B, Boone C. Li Z, et al. Among authors: datti a. Nat Biotechnol. 2011 Apr;29(4):361-7. doi: 10.1038/nbt.1832. Epub 2011 Mar 27. Nat Biotechnol. 2011. PMID: 21441928 Free PMC article.
101 results