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The WD40 domain is required for LRRK2 neurotoxicity.
Jorgensen ND, Peng Y, Ho CC, Rideout HJ, Petrey D, Liu P, Dauer WT. Jorgensen ND, et al. Among authors: dauer wt. PLoS One. 2009 Dec 24;4(12):e8463. doi: 10.1371/journal.pone.0008463. PLoS One. 2009. PMID: 20041156 Free PMC article.
LRRK2 Parkinson disease mutations enhance its microtubule association.
Kett LR, Boassa D, Ho CC, Rideout HJ, Hu J, Terada M, Ellisman M, Dauer WT. Kett LR, et al. Among authors: dauer wt. Hum Mol Genet. 2012 Feb 15;21(4):890-9. doi: 10.1093/hmg/ddr526. Epub 2011 Nov 11. Hum Mol Genet. 2012. PMID: 22080837 Free PMC article.
97 results