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The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions.
Daugaard M, Rohde M, Jäättelä M. Daugaard M, et al. FEBS Lett. 2007 Jul 31;581(19):3702-10. doi: 10.1016/j.febslet.2007.05.039. Epub 2007 May 25. FEBS Lett. 2007. PMID: 17544402 Review.
Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.
Baude A, Aaes TL, Zhai B, Al-Nakouzi N, Oo HZ, Daugaard M, Rohde M, Jäättelä M. Baude A, et al. Among authors: daugaard m. Nucleic Acids Res. 2016 Mar 18;44(5):2214-26. doi: 10.1093/nar/gkv1526. Epub 2015 Dec 31. Nucleic Acids Res. 2016. PMID: 26721387 Free PMC article.
LEDGF (p75) promotes DNA-end resection and homologous recombination.
Daugaard M, Baude A, Fugger K, Povlsen LK, Beck H, Sørensen CS, Petersen NH, Sorensen PH, Lukas C, Bartek J, Lukas J, Rohde M, Jäättelä M. Daugaard M, et al. Nat Struct Mol Biol. 2012 Aug;19(8):803-10. doi: 10.1038/nsmb.2314. Epub 2012 Jul 8. Nat Struct Mol Biol. 2012. PMID: 22773103
BAMLET activates a lysosomal cell death program in cancer cells.
Rammer P, Groth-Pedersen L, Kirkegaard T, Daugaard M, Rytter A, Szyniarowski P, Høyer-Hansen M, Povlsen LK, Nylandsted J, Larsen JE, Jäättelä M. Rammer P, et al. Among authors: daugaard m. Mol Cancer Ther. 2010 Jan;9(1):24-32. doi: 10.1158/1535-7163.MCT-09-0559. Epub 2010 Jan 6. Mol Cancer Ther. 2010. PMID: 20053771
Lens epithelium-derived growth factor is an Hsp70-2 regulated guardian of lysosomal stability in human cancer.
Daugaard M, Kirkegaard-Sørensen T, Ostenfeld MS, Aaboe M, Høyer-Hansen M, Orntoft TF, Rohde M, Jäättelä M. Daugaard M, et al. Cancer Res. 2007 Mar 15;67(6):2559-67. doi: 10.1158/0008-5472.CAN-06-4121. Cancer Res. 2007. PMID: 17363574
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms.
Rohde M, Daugaard M, Jensen MH, Helin K, Nylandsted J, Jäättelä M. Rohde M, et al. Among authors: daugaard m. Genes Dev. 2005 Mar 1;19(5):570-82. doi: 10.1101/gad.305405. Genes Dev. 2005. PMID: 15741319 Free PMC article.
Hsp70-2 is required for tumor cell growth and survival.
Daugaard M, Jäättelä M, Rohde M. Daugaard M, et al. Cell Cycle. 2005 Jul;4(7):877-80. doi: 10.4161/cc.4.7.1838. Epub 2005 Jul 11. Cell Cycle. 2005. PMID: 15970673
Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy.
Farkas T, Daugaard M, Jäättelä M. Farkas T, et al. Among authors: daugaard m. J Biol Chem. 2011 Nov 11;286(45):38904-12. doi: 10.1074/jbc.M111.269134. Epub 2011 Sep 19. J Biol Chem. 2011. PMID: 21930714 Free PMC article.
Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation.
Lallous N, Leblanc E, Munuganti RS, Hassona MD, Nakouzi NA, Awrey S, Morin H, Roshan-Moniri M, Singh K, Lawn S, Yamazaki T, Adomat HH, Andre C, Daugaard M, Young RN, Guns ES, Rennie PS, Cherkasov A. Lallous N, et al. Among authors: daugaard m. Mol Cancer Ther. 2016 Dec;15(12):2936-2945. doi: 10.1158/1535-7163.MCT-16-0354. Epub 2016 Oct 7. Mol Cancer Ther. 2016. PMID: 27765852 Free PMC article.
Dianhydrogalactitol induces replication-dependent DNA damage in tumor cells preferentially resolved by homologous recombination.
Zhai B, Steinø A, Bacha J, Brown D, Daugaard M. Zhai B, et al. Among authors: daugaard m. Cell Death Dis. 2018 Oct 3;9(10):1016. doi: 10.1038/s41419-018-1069-9. Cell Death Dis. 2018. PMID: 30283085 Free PMC article.
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