Daugherty MD - Search Results

1

Experimental determination and system level analysis of essential genes in Escherichia coli MG1655.

Gerdes SY, Scholle MD, Campbell JW, Balázsi G, Ravasz E, Daugherty MD, Somera AL, Kyrpides NC, Anderson I, Gelfand MS, Bhattacharya A, Kapatral V, D'Souza M, Baev MV, Grechkin Y, Mseeh F, Fonstein MY, Overbeek R, Barabási AL, Oltvai ZN, Osterman AL. Gerdes SY, et al. Among authors: daugherty md. J Bacteriol. 2003 Oct;185(19):5673-84. doi: 10.1128/JB.185.19.5673-5684.2003. J Bacteriol. 2003. PMID: 13129938 Free PMC article.

2

From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathways.

Gerdes SY, Scholle MD, D'Souza M, Bernal A, Baev MV, Farrell M, Kurnasov OV, Daugherty MD, Mseeh F, Polanuyer BM, Campbell JW, Anantha S, Shatalin KY, Chowdhury SA, Fonstein MY, Osterman AL. Gerdes SY, et al. Among authors: daugherty md. J Bacteriol. 2002 Aug;184(16):4555-72. doi: 10.1128/JB.184.16.4555-4572.2002. J Bacteriol. 2002. PMID: 12142426 Free PMC article.

3

Archaeal shikimate kinase, a new member of the GHMP-kinase family.

Daugherty M, Vonstein V, Overbeek R, Osterman A. Daugherty M, et al. J Bacteriol. 2001 Jan;183(1):292-300. doi: 10.1128/JB.183.1.292-300.2001. J Bacteriol. 2001. PMID: 11114929 Free PMC article.

4

Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics.

Daugherty M, Polanuyer B, Farrell M, Scholle M, Lykidis A, de Crécy-Lagard V, Osterman A. Daugherty M, et al. J Biol Chem. 2002 Jun 14;277(24):21431-9. doi: 10.1074/jbc.M201708200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923312 Free article.

5

Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.

Zhou T, Daugherty M, Grishin NV, Osterman AL, Zhang H. Zhou T, et al. Structure. 2000 Dec 15;8(12):1247-57. doi: 10.1016/s0969-2126(00)00533-5. Structure. 2000. PMID: 11188689 Free article.

6

Structural basis for the catalysis and substrate specificity of homoserine kinase.

Krishna SS, Zhou T, Daugherty M, Osterman A, Zhang H. Krishna SS, et al. Biochemistry. 2001 Sep 11;40(36):10810-8. doi: 10.1021/bi010851z. Biochemistry. 2001. PMID: 11535056

7

Synthesis and analysis of potential prodrugs of coenzyme A analogues for the inhibition of the histone acetyltransferase p300.

Cebrat M, Kim CM, Thompson PR, Daugherty M, Cole PA. Cebrat M, et al. Bioorg Med Chem. 2003 Jul 31;11(15):3307-13. doi: 10.1016/s0968-0896(03)00265-7. Bioorg Med Chem. 2003. PMID: 12837541

8

Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis.

Fuhrmann CN, Daugherty MD, Agard DA. Fuhrmann CN, et al. Among authors: daugherty md. J Am Chem Soc. 2006 Jul 19;128(28):9086-102. doi: 10.1021/ja057721o. J Am Chem Soc. 2006. PMID: 16834383

9

A single intermolecular contact mediates intramolecular stabilization of both RNA and protein.

Calabro V, Daugherty MD, Frankel AD. Calabro V, et al. Among authors: daugherty md. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6849-54. doi: 10.1073/pnas.0409282102. Epub 2005 Apr 27. Proc Natl Acad Sci U S A. 2005. PMID: 15857951 Free PMC article.

10

An alpha-helical peptidomimetic inhibitor of the HIV-1 Rev-RRE interaction.

Mills NL, Daugherty MD, Frankel AD, Guy RK. Mills NL, et al. Among authors: daugherty md. J Am Chem Soc. 2006 Mar 22;128(11):3496-7. doi: 10.1021/ja0582051. J Am Chem Soc. 2006. PMID: 16536504 Free PMC article.

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