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Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.
Ved HS, Koenig ML, Dave JR, Doctor BP. Ved HS, et al. Among authors: dave jr. Neuroreport. 1997 Mar 3;8(4):963-8. doi: 10.1097/00001756-199703030-00029. Neuroreport. 1997. PMID: 9141073
Selective brain cooling in rats ameliorates intracerebral hemorrhage and edema caused by penetrating brain injury: possible involvement of heme oxygenase-1 expression.
Yao C, Wei G, Lu XC, Yang W, Tortella FC, Dave JR. Yao C, et al. Among authors: dave jr. J Neurotrauma. 2011 Jul;28(7):1237-45. doi: 10.1089/neu.2010.1678. J Neurotrauma. 2011. PMID: 21463155
Mechanism of action for NNZ-2566 anti-inflammatory effects following PBBI involves upregulation of immunomodulator ATF3.
Cartagena CM, Phillips KL, Williams GL, Konopko M, Tortella FC, Dave JR, Schmid KE. Cartagena CM, et al. Among authors: dave jr. Neuromolecular Med. 2013 Sep;15(3):504-14. doi: 10.1007/s12017-013-8236-z. Epub 2013 Jun 14. Neuromolecular Med. 2013. PMID: 23765588
Nefiracetam attenuates post-ischemic nonconvulsive seizures in rats and protects neuronal cell death induced by veratridine and glutamate.
Lu XC, Dave JR, Chen Z, Cao Y, Liao Z, Tortella FC. Lu XC, et al. Among authors: dave jr. Life Sci. 2013 Jun 13;92(22):1055-63. doi: 10.1016/j.lfs.2013.04.004. Epub 2013 Apr 18. Life Sci. 2013. PMID: 23603142
Human amnion-derived multipotent progenitor cell treatment alleviates traumatic brain injury-induced axonal degeneration.
Chen Z, Tortella FC, Dave JR, Marshall VS, Clarke DL, Sing G, Du F, Lu XC. Chen Z, et al. Among authors: dave jr. J Neurotrauma. 2009 Nov;26(11):1987-97. doi: 10.1089/neu.2008.0863. J Neurotrauma. 2009. PMID: 19886807
NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury.
Lu XC, Chen RW, Yao C, Wei H, Yang X, Liao Z, Dave JR, Tortella FC. Lu XC, et al. Among authors: dave jr. J Neurotrauma. 2009 Jan;26(1):141-54. doi: 10.1089/neu.2008.0629. J Neurotrauma. 2009. PMID: 19119917
PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK.
Chen RW, Lu XC, Yao C, Liao Z, Jiang ZG, Wei H, Ghanbari HA, Tortella FC, Dave JR. Chen RW, et al. Among authors: dave jr. Neurosci Lett. 2007 Jul 5;422(1):64-7. doi: 10.1016/j.neulet.2007.06.004. Epub 2007 Jun 8. Neurosci Lett. 2007. PMID: 17600621
Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation.
Chen RW, Williams AJ, Liao Z, Yao C, Tortella FC, Dave JR. Chen RW, et al. Among authors: dave jr. Neurosci Lett. 2007 May 17;418(2):165-9. doi: 10.1016/j.neulet.2007.03.033. Epub 2007 Mar 18. Neurosci Lett. 2007. PMID: 17398001
Down regulation of sodium channel Na(v)1.1 expression by veratridine and its reversal by a novel sodium channel blocker, RS100642, in primary neuronal cultures.
Dave JR, Yao C, Moffett JR, Berti R, Koenig M, Tortella FC. Dave JR, et al. Neurotox Res. 2003;5(3):213-20. doi: 10.1007/BF03033141. Neurotox Res. 2003. PMID: 12835125
Studies on neuronal apoptosis in primary forebrain cultures: neuroprotective/anti-apoptotic action of NR2B NMDA antagonists.
Dave JR, Williams AJ, Moffett JR, Koenig ML, Tortella FC. Dave JR, et al. Neurotox Res. 2003;5(4):255-64. doi: 10.1007/BF03033383. Neurotox Res. 2003. PMID: 12835117
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