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Mammalian heparanase: what is the message?
Vreys V, David G. Vreys V, et al. J Cell Mol Med. 2007 May-Jun;11(3):427-52. doi: 10.1111/j.1582-4934.2007.00039.x. J Cell Mol Med. 2007. PMID: 17635638 Free PMC article. Review.
Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican.
Steinfeld R, Van Den Berghe H, David G. Steinfeld R, et al. J Cell Biol. 1996 Apr;133(2):405-16. doi: 10.1083/jcb.133.2.405. J Cell Biol. 1996. PMID: 8609172 Free PMC article.
Eisinger, G. David, and A. Yayon. 1994. Cell 79:1005-1013). In alternative tests to establish whether cell-surface proteoglycans can support the formation of the required complexes, K562 cells were first transfected with the IIIc splice variant of FGFR1 and then tra …
Eisinger, G. David, and A. Yayon. 1994. Cell 79:1005-1013). In alternative tests to establish whether cell-surface proteoglyca …
The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling.
Luyten A, Mortier E, Van Campenhout C, Taelman V, Degeest G, Wuytens G, Lambaerts K, David G, Bellefroid EJ, Zimmermann P. Luyten A, et al. Mol Biol Cell. 2008 Apr;19(4):1594-604. doi: 10.1091/mbc.e07-08-0832. Epub 2008 Feb 6. Mol Biol Cell. 2008. PMID: 18256285 Free PMC article.
Heparanase activates the syndecan-syntenin-ALIX exosome pathway.
Roucourt B, Meeussen S, Bao J, Zimmermann P, David G. Roucourt B, et al. Cell Res. 2015 Apr;25(4):412-28. doi: 10.1038/cr.2015.29. Epub 2015 Mar 3. Cell Res. 2015. PMID: 25732677 Free PMC article.
Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans.
Vreys V, Delande N, Zhang Z, Coomans C, Roebroek A, Dürr J, David G. Vreys V, et al. J Biol Chem. 2005 Sep 30;280(39):33141-8. doi: 10.1074/jbc.M503007200. Epub 2005 Jul 26. J Biol Chem. 2005. PMID: 16046412
Syndecan 3 intramembrane proteolysis is presenilin/gamma-secretase-dependent and modulates cytosolic signaling.
Schulz JG, Annaert W, Vandekerckhove J, Zimmermann P, De Strooper B, David G. Schulz JG, et al. J Biol Chem. 2003 Dec 5;278(49):48651-7. doi: 10.1074/jbc.M308424200. Epub 2003 Sep 22. J Biol Chem. 2003. PMID: 14504279
PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane.
Zimmermann P, Meerschaert K, Reekmans G, Leenaerts I, Small JV, Vandekerckhove J, David G, Gettemans J. Zimmermann P, et al. Mol Cell. 2002 Jun;9(6):1215-25. doi: 10.1016/s1097-2765(02)00549-x. Mol Cell. 2002. PMID: 12086619
Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements.
De Cat B, Muyldermans SY, Coomans C, Degeest G, Vanderschueren B, Creemers J, Biemar F, Peers B, David G. De Cat B, et al. J Cell Biol. 2003 Nov 10;163(3):625-35. doi: 10.1083/jcb.200302152. J Cell Biol. 2003. PMID: 14610063 Free PMC article.
Heparanase tailors syndecan for exosome production.
David G, Zimmermann P. David G, et al. Mol Cell Oncol. 2015 Nov 11;3(3):e1047556. doi: 10.1080/23723556.2015.1047556. eCollection 2016 May. Mol Cell Oncol. 2015. PMID: 27314072 Free PMC article.
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