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The proteasomal system and HNE-modified proteins.
Grune T, Davies KJ. Grune T, et al. Among authors: davies kj. Mol Aspects Med. 2003 Aug-Oct;24(4-5):195-204. doi: 10.1016/s0098-2997(03)00014-1. Mol Aspects Med. 2003. PMID: 12892997 Review.
Age-related changes in protein oxidation and proteolysis in mammalian cells.
Grune T, Shringarpure R, Sitte N, Davies K. Grune T, et al. Among authors: davies k. J Gerontol A Biol Sci Med Sci. 2001 Nov;56(11):B459-67. doi: 10.1093/gerona/56.11.b459. J Gerontol A Biol Sci Med Sci. 2001. PMID: 11682566 Review.
Protein oxidation and degradation during postmitotic senescence.
Grune T, Merker K, Jung T, Sitte N, Davies KJ. Grune T, et al. Among authors: davies kj. Free Radic Biol Med. 2005 Nov 1;39(9):1208-15. doi: 10.1016/j.freeradbiomed.2005.06.009. Free Radic Biol Med. 2005. PMID: 16214036
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.
Grune T, Jung T, Merker K, Davies KJ. Grune T, et al. Among authors: davies kj. Int J Biochem Cell Biol. 2004 Dec;36(12):2519-30. doi: 10.1016/j.biocel.2004.04.020. Int J Biochem Cell Biol. 2004. PMID: 15325589 Review.
Selective degradation of oxidatively modified protein substrates by the proteasome.
Grune T, Merker K, Sandig G, Davies KJ. Grune T, et al. Among authors: davies kj. Biochem Biophys Res Commun. 2003 Jun 6;305(3):709-18. doi: 10.1016/s0006-291x(03)00809-x. Biochem Biophys Res Commun. 2003. PMID: 12763051 Review.
Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress.
Poppek D, Keck S, Ermak G, Jung T, Stolzing A, Ullrich O, Davies KJ, Grune T. Poppek D, et al. Among authors: davies kj. Biochem J. 2006 Dec 15;400(3):511-20. doi: 10.1042/BJ20060463. Biochem J. 2006. PMID: 16939415 Free PMC article.
Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.
Grune T, Botzen D, Engels M, Voss P, Kaiser B, Jung T, Grimm S, Ermak G, Davies KJ. Grune T, et al. Among authors: davies kj. Arch Biochem Biophys. 2010 Aug 15;500(2):181-8. doi: 10.1016/j.abb.2010.05.008. Epub 2010 May 15. Arch Biochem Biophys. 2010. PMID: 20478262 Free PMC article.
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