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Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Davies SP, Reddy H, Caivano M, Cohen P. Davies SP, et al. Biochem J. 2000 Oct 1;351(Pt 1):95-105. doi: 10.1042/0264-6021:3510095. Biochem J. 2000. PMID: 10998351 Free PMC article.
AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge.
Hardie DG, Salt IP, Hawley SA, Davies SP. Hardie DG, et al. Among authors: davies sp. Biochem J. 1999 Mar 15;338 ( Pt 3)(Pt 3):717-22. Biochem J. 1999. PMID: 10051444 Free PMC article.
Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.
Cheung PC, Salt IP, Davies SP, Hardie DG, Carling D. Cheung PC, et al. Among authors: davies sp. Biochem J. 2000 Mar 15;346 Pt 3(Pt 3):659-69. Biochem J. 2000. PMID: 10698692 Free PMC article.
Analysis of the role of the AMP-activated protein kinase in the response to cellular stress.
Hardie DG, Salt IP, Davies SP. Hardie DG, et al. Among authors: davies sp. Methods Mol Biol. 2000;99:63-74. doi: 10.1385/1-59259-054-3:63. Methods Mol Biol. 2000. PMID: 10909077 Review. No abstract available.
Regulation of lipid metabolism by the AMP-activated protein kinase.
Hardie DG, Corton J, Ching YP, Davies SP, Hawley S. Hardie DG, et al. Among authors: davies sp. Biochem Soc Trans. 1997 Nov;25(4):1229-31. doi: 10.1042/bst0251229. Biochem Soc Trans. 1997. PMID: 9449981 Review. No abstract available.
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase.
Hawley SA, Davison M, Woods A, Davies SP, Beri RK, Carling D, Hardie DG. Hawley SA, et al. Among authors: davies sp. J Biol Chem. 1996 Nov 1;271(44):27879-87. doi: 10.1074/jbc.271.44.27879. J Biol Chem. 1996. PMID: 8910387
Analysis of the specificity of the AMP-activated protein kinase by site-directed mutagenesis of bacterially expressed 3-hydroxy 3-methylglutaryl-CoA reductase, using a single primer variant of the unique-site-elimination method.
Ching YP, Davies SP, Hardie DG. Ching YP, et al. Among authors: davies sp. Eur J Biochem. 1996 May 1;237(3):800-8. doi: 10.1111/j.1432-1033.1996.0800p.x. Eur J Biochem. 1996. PMID: 8647128
5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.
Davies SP, Helps NR, Cohen PT, Hardie DG. Davies SP, et al. FEBS Lett. 1995 Dec 27;377(3):421-5. doi: 10.1016/0014-5793(95)01368-7. FEBS Lett. 1995. PMID: 8549768
Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure.
Davies SP, Hawley SA, Woods A, Carling D, Haystead TA, Hardie DG. Davies SP, et al. Eur J Biochem. 1994 Jul 15;223(2):351-7. doi: 10.1111/j.1432-1033.1994.tb19001.x. Eur J Biochem. 1994. PMID: 8055903
Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay.
Davies SP, Carling D, Hardie DG. Davies SP, et al. Eur J Biochem. 1989 Dec 8;186(1-2):123-8. doi: 10.1111/j.1432-1033.1989.tb15185.x. Eur J Biochem. 1989. PMID: 2574667
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