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Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.
Nizami S, Arunasalam K, Green J, Cook J, Lawrence CB, Zarganes-Tzitzikas T, Davis JB, Di Daniel E, Brough D. Nizami S, et al. Among authors: davis jb. Immunology. 2021 Jan;162(1):84-91. doi: 10.1111/imm.13267. Epub 2020 Oct 30. Immunology. 2021. PMID: 32954500 Free PMC article.
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hall-Roberts H, Agarwal D, Obst J, Smith TB, Monzón-Sandoval J, Di Daniel E, Webber C, James WS, Mead E, Davis JB, Cowley SA. Hall-Roberts H, et al. Among authors: davis jb. Alzheimers Res Ther. 2020 Nov 16;12(1):151. doi: 10.1186/s13195-020-00709-z. Alzheimers Res Ther. 2020. PMID: 33198789 Free PMC article.
Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Szykowska A, Chen Y, Smith TB, Preger C, Yang J, Qian D, Mukhopadhyay SM, Wigren E, Neame SJ, Gräslund S, Persson H, Atkinson PJ, Di Daniel E, Mead E, Wang J, Davis JB, Burgess-Brown NA, Bullock AN. Szykowska A, et al. Among authors: davis jb. Structure. 2021 Jun 25:S0969-2126(21)00214-8. doi: 10.1016/j.str.2021.06.010. Online ahead of print. Structure. 2021. PMID: 34233201 Free article.
Reverse Phase Protein Arrays.
Davis JB, Andes S, Espina V. Davis JB, et al. Methods Mol Biol. 2021;2237:103-122. doi: 10.1007/978-1-0716-1064-0_9. Methods Mol Biol. 2021. PMID: 33237412
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