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Hypoxia signalling in cancer and approaches to enforce tumour regression.
Pouysségur J, Dayan F, Mazure NM. Pouysségur J, et al. Among authors: dayan f. Nature. 2006 May 25;441(7092):437-43. doi: 10.1038/nature04871. Nature. 2006. PMID: 16724055 Review.
The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis.
Pelletier J, Dayan F, Durivault J, Ilc K, Pécou E, Pouysségur J, Mazure NM. Pelletier J, et al. Among authors: dayan f. Oncogene. 2012 Jun 14;31(24):2989-3001. doi: 10.1038/onc.2011.471. Epub 2011 Oct 17. Oncogene. 2012. PMID: 22002313
A dialogue between the hypoxia-inducible factor and the tumor microenvironment.
Dayan F, Mazure NM, Brahimi-Horn MC, Pouysségur J. Dayan F, et al. Cancer Microenviron. 2008 Dec;1(1):53-68. doi: 10.1007/s12307-008-0006-3. Epub 2008 Mar 19. Cancer Microenviron. 2008. PMID: 19308685 Free PMC article.
Gene regulation in response to graded hypoxia: the non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway.
Dayan F, Monticelli M, Pouysségur J, Pécou E. Dayan F, et al. J Theor Biol. 2009 Jul 21;259(2):304-16. doi: 10.1016/j.jtbi.2009.03.009. Epub 2009 Mar 17. J Theor Biol. 2009. PMID: 19298827
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.
Chiche J, Ilc K, Laferrière J, Trottier E, Dayan F, Mazure NM, Brahimi-Horn MC, Pouysségur J. Chiche J, et al. Among authors: dayan f. Cancer Res. 2009 Jan 1;69(1):358-68. doi: 10.1158/0008-5472.CAN-08-2470. Cancer Res. 2009. PMID: 19118021
Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
Dayan F, Bilton RL, Laferrière J, Trottier E, Roux D, Pouyssegur J, Mazure NM. Dayan F, et al. J Cell Physiol. 2009 Jan;218(1):167-74. doi: 10.1002/jcp.21584. J Cell Physiol. 2009. PMID: 18781596
HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs.
Mazure NM, Brahimi-Horn MC, Berta MA, Benizri E, Bilton RL, Dayan F, Ginouvès A, Berra E, Pouysségur J. Mazure NM, et al. Among authors: dayan f. Biochem Pharmacol. 2004 Sep 15;68(6):971-80. doi: 10.1016/j.bcp.2004.04.022. Biochem Pharmacol. 2004. PMID: 15313390 Review.
The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
Dayan F, Roux D, Brahimi-Horn MC, Pouyssegur J, Mazure NM. Dayan F, et al. Cancer Res. 2006 Apr 1;66(7):3688-98. doi: 10.1158/0008-5472.CAN-05-4564. Cancer Res. 2006. PMID: 16585195
The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
Pez F, Dayan F, Durivault J, Kaniewski B, Aimond G, Le Provost GS, Deux B, Clézardin P, Sommer P, Pouysségur J, Reynaud C. Pez F, et al. Among authors: dayan f. Cancer Res. 2011 Mar 1;71(5):1647-57. doi: 10.1158/0008-5472.CAN-10-1516. Epub 2011 Jan 14. Cancer Res. 2011. PMID: 21239473
Conservation and divergence in sorgoleone production of sorghum species.
Besançon TE, Dayan FE, Gannon TW, Everman WJ. Besançon TE, et al. Among authors: dayan fe. J Environ Qual. 2020 Mar;49(2):368-377. doi: 10.1002/jeq2.20038. Epub 2020 Mar 4. J Environ Qual. 2020. PMID: 33016416
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