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Prognostic significance of proliferative and apoptotic markers in oral tongue squamous cell carcinomas.
Xie X, De Angelis P, Clausen OP, Boysen M. Xie X, et al. Among authors: de angelis p. Oral Oncol. 1999 Sep;35(5):502-9. doi: 10.1016/s1368-8375(99)00024-x. Oral Oncol. 1999. PMID: 10694951
Bax expression correlated positively with AI (p = 0.0122). Ki67 correlated with both pAgNOR > 1 (p = 0.0042) and mAgNOR (p = 0.0189). ...High values for Ki67, pAgNOR > 1 and mAgNOR correlated with poor prognosis (p = 0.0021, p = 0.0001 and …
Bax expression correlated positively with AI (p = 0.0122). Ki67 correlated with both pAgNOR > 1 (p = 0.0042) and mAgNOR ( …
Retinoic acid provokes a regeneration-like proliferative response in murine epidermis. A bivariate DNA/bromodeoxyuridine flow cytometric study.
Lützow-Holm C, De Angelis P, Clausen OP. Lützow-Holm C, et al. Among authors: de angelis p. Arch Dermatol Res. 1992;284(7):418-23. doi: 10.1007/BF00372073. Arch Dermatol Res. 1992. PMID: 1288424
Binding diversity of antibodies against external and internal epitopes of the multidrug resistance gene product P-glycoprotein.
Lehne G, De Angelis P, Clausen OP, Egeland T, Tsuruo T, Rugstad HE. Lehne G, et al. Among authors: de angelis p. Cytometry. 1995 Jul 1;20(3):228-37. doi: 10.1002/cyto.990200306. Cytometry. 1995. PMID: 7587708
P-glycoprotein (Pgp) is a trans-membraneous protein that is associated with multidrug resistance (MDR) in human cancer, including hepatocellular carcinomas and leukemias. ...
P-glycoprotein (Pgp) is a trans-membraneous protein that is associated with multidrug resistance (MDR) in human cancer, including hep
1,25-Dihydroxyvitamin D3 and the vitamin D analogue KH1060 induce hyperproliferation in normal mouse epidermis. A BrdUrd/DNA flow cytometric study.
Lützow-Holm C, De Angelis P, Grøsvik H, Clausen OP. Lützow-Holm C, et al. Among authors: de angelis p. Exp Dermatol. 1993 Jun;2(3):113-20. doi: 10.1111/j.1600-0625.1993.tb00018.x. Exp Dermatol. 1993. PMID: 8162327
NO38 expression and nucleolar counts are correlated with cellular DNA content but not with proliferation parameters in colorectal carcinomas.
De Angelis PM, Stokke T, Clausen OP. De Angelis PM, et al. Mol Pathol. 1997 Aug;50(4):201-8. doi: 10.1136/mp.50.4.201. Mol Pathol. 1997. PMID: 9350304 Free PMC article.
NO38 expression and numbers of nucleoli correlated significantly (r = 0.52, p = 0.01). There were, however, no significant correlations between these nucleolar parameters and either the sizes of tumour S phase fractions or Ki67 labelling indices. ...
NO38 expression and numbers of nucleoli correlated significantly (r = 0.52, p = 0.01). There were, however, no significant correlatio …
Bax expression has prognostic significance that is enhanced when combined with AgNOR counts in glottic carcinomas.
Xie X, Clausen OP, De Angelis P, Boysen M. Xie X, et al. Among authors: de angelis p. Br J Cancer. 1998 Jul;78(1):100-5. doi: 10.1038/bjc.1998.449. Br J Cancer. 1998. PMID: 9662258 Free PMC article.
Low Bax scores correlated significantly with poor prognosis (P = 0.0106). For mAgNOR and pAgNOR>1, high values correlated with poor prognosis (P = 0.0185 and P = 0.0003 respectively). A combined parameter, for which the Bax score was subtracted from the Ag …
Low Bax scores correlated significantly with poor prognosis (P = 0.0106). For mAgNOR and pAgNOR>1, high values correlated with poo …
Association of p53 accumulation with TP53 mutations, loss of heterozygosity at 17p13, and DNA ploidy status in 273 colorectal carcinomas.
Clausen OP, Lothe RA, Børresen-Dale AL, De Angelis P, Chen Y, Rognum TO, Meling GI. Clausen OP, et al. Among authors: de angelis p. Diagn Mol Pathol. 1998 Aug;7(4):215-23. doi: 10.1097/00019606-199808000-00006. Diagn Mol Pathol. 1998. PMID: 9917132

TP53 mutations were significantly associated with DNA aneuploidy (P < 0.00001), and a nonrandom distribution of TP53 gene alterations among diploid (DI = 1), hyperdiploid (1.0 < DI < 1.3), and highly aneuploid (DI > 1.3) tumors indicates that DNA hyperdiploid t

TP53 mutations were significantly associated with DNA aneuploidy (P < 0.00001), and a nonrandom distribution of TP53 gene alterati

Apoptosis and expression of Bax, Bcl-x, and Bcl-2 apoptotic regulatory proteins in colorectal carcinomas, and association with p53 genotype/phenotype.
De Angelis PM, Stokke T, Thorstensen L, Lothe RA, Clausen OP. De Angelis PM, et al. Mol Pathol. 1998 Oct;51(5):254-61. doi: 10.1136/mp.51.5.254. Mol Pathol. 1998. PMID: 10193519 Free PMC article.
The prognostic value of spontaneous apoptosis, Bax, Bcl-2, and p53 in oral squamous cell carcinoma of the tongue.
Xie X, Clausen OP, De Angelis P, Boysen M. Xie X, et al. Among authors: de angelis p. Cancer. 1999 Sep 15;86(6):913-20. doi: 10.1002/(sici)1097-0142(19990915)86:6<913::aid-cncr4>3.0.co;2-a. Cancer. 1999. PMID: 10491515
RESULTS: High AI was significantly associated with high Bax expression (P = 0.0122) and highly differentiated tumors (P = 0.0062). ...Whereas low AI scores and low Bax expression correlated significantly with poor prognosis (P = 0.0053 and P = 0.0012, …
RESULTS: High AI was significantly associated with high Bax expression (P = 0.0122) and highly differentiated tumors (P = 0.00 …
Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma.
Stokke T, Galteland E, Holte H, Smedshammer L, Suo Z, Smeland EB, Børresen-Dale AL, DeAngelis P, Steen HB. Stokke T, et al. Int J Cancer. 2000 Jul 20;89(4):313-24. doi: 10.1002/1097-0215(20000720)89:4<313::aid-ijc1>3.0.co;2-d. Int J Cancer. 2000. PMID: 10956404
Tumors from the 3 latter groups had higher median S phase fractions (5%, 7.6%, and 5%, respectively, p<0.02) than the cases without any aberrations (1.1%), and survival time for these patients was much shorter (relative risks of 5.9, 8.9, and 6.6, respectively, p
Tumors from the 3 latter groups had higher median S phase fractions (5%, 7.6%, and 5%, respectively, p<0.02) than the cases withou …
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