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Suppression of the clinical and cytokine response to endotoxin by RWJ-67657, a p38 mitogen-activated protein-kinase inhibitor, in healthy human volunteers.
Fijen JW, Zijlstra JG, De Boer P, Spanjersberg R, Tervaert JW, Van Der Werf TS, Ligtenberg JJ, Tulleken JE. Fijen JW, et al. Among authors: de boer p. Clin Exp Immunol. 2001 Apr;124(1):16-20. doi: 10.1046/j.1365-2249.2001.01485.x. Clin Exp Immunol. 2001. PMID: 11359438 Free PMC article. Clinical Trial.
Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor.
Westra J, Doornbos-van der Meer B, de Boer P, van Leeuwen MA, van Rijswijk MH, Limburg PC. Westra J, et al. Among authors: de boer p. Arthritis Res Ther. 2004;6(4):R384-92. doi: 10.1186/ar1204. Epub 2004 Jun 21. Arthritis Res Ther. 2004. PMID: 15225374 Free PMC article.
Pharmacological fMRI: Effects of subanesthetic ketamine on resting-state functional connectivity in the default mode network, salience network, dorsal attention network and executive control network.
Mueller F, Musso F, London M, de Boer P, Zacharias N, Winterer G. Mueller F, et al. Among authors: de boer p. Neuroimage Clin. 2018 Jun 1;19:745-757. doi: 10.1016/j.nicl.2018.05.037. eCollection 2018. Neuroimage Clin. 2018. PMID: 30003027 Free PMC article. Clinical Trial.
Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants.
Timmers M, Ravenstijn P, Xi L, Triana-Baltzer G, Furey M, Van Hemelryck S, Biewenga J, Ceusters M, Bhattacharya A, van den Boer M, van Nueten L, de Boer P. Timmers M, et al. Among authors: de boer p. J Psychopharmacol. 2018 Dec;32(12):1341-1350. doi: 10.1177/0269881118800067. Epub 2018 Sep 27. J Psychopharmacol. 2018. PMID: 30260294 Clinical Trial.
451 results