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2,157 results
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Evaluating phenotype and genotype of drug-resistant strains in herpesviruses.
Andrei G, Fiten P, De Clercq E, Snoeck R, Opdenakker G. Andrei G, et al. Among authors: de clercq e. Mol Biotechnol. 2001 Jun;18(2):155-67. doi: 10.1385/mb:18:2:155. Mol Biotechnol. 2001. PMID: 11471457
Selective anti-herpesvirus agents.
De Clercq E. De Clercq E. Antivir Chem Chemother. 2013 Jan 23;23(3):93-101. doi: 10.3851/IMP2533. Antivir Chem Chemother. 2013. PMID: 23343513 Review.
Synthesis and antiviral activity of some 5'-N-phthaloyl-3'-azido-2',3'-dideoxythymidine analogues.
Balzarini J, De Clercq E, Kaminska B, Orzeszko A. Balzarini J, et al. Among authors: de clercq e. Antivir Chem Chemother. 2003 May;14(3):139-44. doi: 10.1177/095632020301400303. Antivir Chem Chemother. 2003. PMID: 14521330
The unabated synthesis of new nucleoside analogues with antiviral potential: a tribute to Morris J. Robins.
De Clercq E. De Clercq E. Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):586-600. doi: 10.1080/15257770903054159. Nucleosides Nucleotides Nucleic Acids. 2009. PMID: 20183603 Review.
A time-of-drug addition approach to target identification of antiviral compounds.
Daelemans D, Pauwels R, De Clercq E, Pannecouque C. Daelemans D, et al. Among authors: de clercq e. Nat Protoc. 2011 Jun;6(6):925-33. doi: 10.1038/nprot.2011.330. Epub 2011 Jun 2. Nat Protoc. 2011. PMID: 21637207 Free PMC article.
In search of a selective therapy of viral infections.
De Clercq E. De Clercq E. Antiviral Res. 2010 Jan;85(1):19-24. doi: 10.1016/j.antiviral.2009.10.005. Epub 2009 Oct 21. Antiviral Res. 2010. PMID: 19852983 Review.
Looking back in 2009 at the dawning of antiviral therapy now 50 years ago an historical perspective.
De Clercq E. De Clercq E. Adv Virus Res. 2009;73:1-53. doi: 10.1016/S0065-3527(09)73001-5. Adv Virus Res. 2009. PMID: 19695380
Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.
De Palma AM, Thibaut HJ, van der Linden L, Lanke K, Heggermont W, Ireland S, Andrews R, Arimilli M, Al-Tel TH, De Clercq E, van Kuppeveld F, Neyts J. De Palma AM, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 2009 May;53(5):1850-7. doi: 10.1128/AAC.00934-08. Epub 2009 Feb 23. Antimicrob Agents Chemother. 2009. PMID: 19237651 Free PMC article.
The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C.
De Palma AM, Heggermont W, Lanke K, Coutard B, Bergmann M, Monforte AM, Canard B, De Clercq E, Chimirri A, Pürstinger G, Rohayem J, van Kuppeveld F, Neyts J. De Palma AM, et al. Among authors: de clercq e. J Virol. 2008 May;82(10):4720-30. doi: 10.1128/JVI.01338-07. Epub 2008 Mar 12. J Virol. 2008. PMID: 18337578 Free PMC article.
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
Andrei G, Fiten P, Froeyen M, De Clercq E, Opdenakker G, Snoeck R. Andrei G, et al. Among authors: de clercq e. Antivir Ther. 2007;12(5):719-32. Antivir Ther. 2007. PMID: 17713155
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