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Parkinson's disease: genetics and pathogenesis.
Shulman JM, De Jager PL, Feany MB. Shulman JM, et al. Annu Rev Pathol. 2011;6:193-222. doi: 10.1146/annurev-pathol-011110-130242. Annu Rev Pathol. 2011. PMID: 21034221 Review.
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility.
Reich D, Patterson N, De Jager PL, McDonald GJ, Waliszewska A, Tandon A, Lincoln RR, DeLoa C, Fruhan SA, Cabre P, Bera O, Semana G, Kelly MA, Francis DA, Ardlie K, Khan O, Cree BA, Hauser SL, Oksenberg JR, Hafler DA. Reich D, et al. Nat Genet. 2005 Oct;37(10):1113-8. doi: 10.1038/ng1646. Epub 2005 Sep 25. Nat Genet. 2005. PMID: 16186815
Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis.
De Jager PL, Sawcer S, Waliszewska A, Farwell L, Wild G, Cohen A, Langelier D, Bitton A, Compston A, Hafler DA, Rioux JD. De Jager PL, et al. Eur J Hum Genet. 2006 Mar;14(3):317-21. doi: 10.1038/sj.ejhg.5201548. Eur J Hum Genet. 2006. PMID: 16391555
New therapeutic approaches for multiple sclerosis.
De Jager PL, Hafler DA. De Jager PL, et al. Annu Rev Med. 2007;58:417-32. doi: 10.1146/ Annu Rev Med. 2007. PMID: 17217332 Review.
Risk alleles for multiple sclerosis identified by a genomewide study.
International Multiple Sclerosis Genetics Consortium, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, Hauser SL. International Multiple Sclerosis Genetics Consortium, et al. N Engl J Med. 2007 Aug 30;357(9):851-62. doi: 10.1056/NEJMoa073493. Epub 2007 Jul 29. N Engl J Med. 2007. PMID: 17660530
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.
Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S; International Multiple Sclerosis Genetics Consortium, De Jager PL, Wicker LS, Todd JA, Hafler DA. Maier LM, et al. PLoS Genet. 2009 Jan;5(1):e1000322. doi: 10.1371/journal.pgen.1000322. Epub 2009 Jan 2. PLoS Genet. 2009. PMID: 19119414 Free PMC article.
Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.
Maier LM, Anderson DE, Severson CA, Baecher-Allan C, Healy B, Liu DV, Wittrup KD, De Jager PL, Hafler DA. Maier LM, et al. J Immunol. 2009 Feb 1;182(3):1541-7. doi: 10.4049/jimmunol.182.3.1541. J Immunol. 2009. PMID: 19155502 Free PMC article.
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S; International MS Genetics Consortium, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR. De Jager PL, et al. Nat Genet. 2009 Jul;41(7):776-82. doi: 10.1038/ng.401. Epub 2009 Jun 14. Nat Genet. 2009. PMID: 19525953 Free PMC article.
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