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Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes.
Sabbisetti VS, Waikar SS, Antoine DJ, Smiles A, Wang C, Ravisankar A, Ito K, Sharma S, Ramadesikan S, Lee M, Briskin R, De Jager PL, Ngo TT, Radlinski M, Dear JW, Park KB, Betensky R, Krolewski AS, Bonventre JV. Sabbisetti VS, et al. Among authors: de jager pl. J Am Soc Nephrol. 2014 Oct;25(10):2177-86. doi: 10.1681/ASN.2013070758. Epub 2014 Jun 5. J Am Soc Nephrol. 2014. PMID: 24904085 Free PMC article.
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S; International MS Genetics Consortium; Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR. De Jager PL, et al. Among authors: de bakker pi. Nat Genet. 2009 Jul;41(7):776-82. doi: 10.1038/ng.401. Epub 2009 Jun 14. Nat Genet. 2009. PMID: 19525953 Free PMC article.
Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus.
Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Ottoboni L, et al. Among authors: de jager pl. Neurology. 2013 Nov 26;81(22):1891-9. doi: 10.1212/01.wnl.0000436612.66328.8a. Epub 2013 Oct 30. Neurology. 2013. PMID: 24174586 Free PMC article.
Evaluating more naturalistic outcome measures: A 1-year smartphone study in multiple sclerosis.
Bove R, White CC, Giovannoni G, Glanz B, Golubchikov V, Hujol J, Jennings C, Langdon D, Lee M, Legedza A, Paskavitz J, Prasad S, Richert J, Robbins A, Roberts S, Weiner H, Ramachandran R, Botfield M, De Jager PL. Bove R, et al. Among authors: de jager pl. Neurol Neuroimmunol Neuroinflamm. 2015 Oct 15;2(6):e162. doi: 10.1212/NXI.0000000000000162. eCollection 2015 Dec. Neurol Neuroimmunol Neuroinflamm. 2015. PMID: 26516627 Free PMC article.
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes.
Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, McCabe C, Paik HI, Srivastava GP, Raychaudhuri S, Hafler DA, Koller D, Regev A, Hacohen N, Mathis D, Benoist C, Stranger BE, De Jager PL. Raj T, et al. Among authors: de jager pl. Science. 2014 May 2;344(6183):519-23. doi: 10.1126/science.1249547. Science. 2014. PMID: 24786080 Free PMC article.
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.
Maier LM, Lowe CE, Cooper J, Downes K, Anderson DE, Severson C, Clark PM, Healy B, Walker N, Aubin C, Oksenberg JR, Hauser SL, Compston A, Sawcer S; International Multiple Sclerosis Genetics Consortium; De Jager PL, Wicker LS, Todd JA, Hafler DA. Maier LM, et al. Among authors: de jager pl. PLoS Genet. 2009 Jan;5(1):e1000322. doi: 10.1371/journal.pgen.1000322. Epub 2009 Jan 2. PLoS Genet. 2009. PMID: 19119414 Free PMC article.
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A; Alzheimer Disease Neuroimaging Initiative; Morris MC, Evans DA, Johnson K, Sperling RA, Schneider JA, Bennett DA, De Jager PL. Bradshaw EM, et al. Among authors: de jager pl. Nat Neurosci. 2013 Jul;16(7):848-50. doi: 10.1038/nn.3435. Epub 2013 May 23. Nat Neurosci. 2013. PMID: 23708142 Free PMC article.
Common genetic variants modulate pathogen-sensing responses in human dendritic cells.
Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler DA, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N. Lee MN, et al. Among authors: de jager pl. Science. 2014 Mar 7;343(6175):1246980. doi: 10.1126/science.1246980. Science. 2014. PMID: 24604203 Free PMC article.
548 results