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Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory Pathways in Macrophages.
Ramírez CM, Torrecilla-Parra M, Pardo-Marqués V, de-Frutos MF, Pérez-García A, Tabraue C, de la Rosa JV, Martín-Rodriguez P, Díaz-Sarmiento M, Nuñez U, Orizaola MC, Través PG, Camps M, Boscá L, Castrillo A. Ramírez CM, et al. Among authors: de la rosa jv. Front Endocrinol (Lausanne). 2021 May 27;12:635923. doi: 10.3389/fendo.2021.635923. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34122329 Free PMC article.
The nuclear receptor LXRα controls the functional specialization of splenic macrophages.
A-Gonzalez N, Guillen JA, Gallardo G, Diaz M, de la Rosa JV, Hernandez IH, Casanova-Acebes M, Lopez F, Tabraue C, Beceiro S, Hong C, Lara PC, Andujar M, Arai S, Miyazaki T, Li S, Corbi AL, Tontonoz P, Hidalgo A, Castrillo A. A-Gonzalez N, et al. Among authors: de la rosa jv. Nat Immunol. 2013 Aug;14(8):831-9. doi: 10.1038/ni.2622. Epub 2013 Jun 16. Nat Immunol. 2013. PMID: 23770640 Free PMC article.
Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation.
Gage MC, Bécares N, Louie R, Waddington KE, Zhang Y, Tittanegro TH, Rodríguez-Lorenzo S, Jathanna A, Pourcet B, Pello OM, De la Rosa JV, Castrillo A, Pineda-Torra I. Gage MC, et al. Among authors: de la rosa jv. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6556-E6565. doi: 10.1073/pnas.1721245115. Epub 2018 Jun 27. Proc Natl Acad Sci U S A. 2018. PMID: 29950315 Free PMC article.
Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages.
González de la Aleja A, Herrero C, Torres-Torresano M, de la Rosa JV, Alonso B, Capa-Sardón E, Muller IB, Jansen G, Puig-Kröger A, Vega MA, Castrillo A, Corbí ÁL. González de la Aleja A, et al. Among authors: de la rosa jv. Front Immunol. 2022 Feb 24;13:835478. doi: 10.3389/fimmu.2022.835478. eCollection 2022. Front Immunol. 2022. PMID: 35280993 Free PMC article.
20 results