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Page 1
Brain Tumor Biobank Development for Precision Medicine: Role of the Neurosurgeon.
Darrigues E, Elberson BW, De Loose A, Lee MP, Green E, Benton AM, Sink LG, Scott H, Gokden M, Day JD, Rodriguez A. Darrigues E, et al. Among authors: de loose a. Front Oncol. 2021 Apr 26;11:662260. doi: 10.3389/fonc.2021.662260. eCollection 2021. Front Oncol. 2021. PMID: 33981610 Free PMC article.
A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma.
Wongsurawat T, Jenjaroenpun P, De Loose A, Alkam D, Ussery DW, Nookaew I, Leung YK, Ho SM, Day JD, Rodriguez A. Wongsurawat T, et al. Among authors: de loose a. Acta Neuropathol Commun. 2020 Jun 20;8(1):87. doi: 10.1186/s40478-020-00963-0. Acta Neuropathol Commun. 2020. PMID: 32563269 Free PMC article.
Genomic and Transcriptomic Profiling of Brain Metastases.
Wardell CP, Darrigues E, De Loose A, Lee MP, Gokden M, Makhoul I, Tackett AJ, Rodriguez A. Wardell CP, et al. Among authors: de loose a. Cancers (Basel). 2021 Nov 9;13(22):5598. doi: 10.3390/cancers13225598. Cancers (Basel). 2021. PMID: 34830758 Free PMC article.
A Functional Precision Medicine Pipeline Combines Comparative Transcriptomics and Tumor Organoid Modeling to Identify Bespoke Treatment Strategies for Glioblastoma.
Reed MR, Lyle AG, De Loose A, Maddukuri L, Learned K, Beale HC, Kephart ET, Cheney A, van den Bout A, Lee MP, Hundley KN, Smith AM, DesRochers TM, Vibat CRT, Gokden M, Salama S, Wardell CP, Eoff RL, Vaske OM, Rodriguez A. Reed MR, et al. Among authors: de loose a. Cells. 2021 Dec 2;10(12):3400. doi: 10.3390/cells10123400. Cells. 2021. PMID: 34943910 Free PMC article.
Synthesis and Anti-Melanoma Activity of Acryloyl Pyridinone Analogues.
Urbaniak A, Bathula C, Chauhan J, Rai P, Thammathong J, Clark C, Heflin B, De Loose A, Avaritt N, Rodriguez A, Tackett AJ, Sen S, Banerjee S. Urbaniak A, et al. Among authors: de loose a. Chem Biodivers. 2023 Dec;20(12):e202301550. doi: 10.1002/cbdv.202301550. Epub 2023 Nov 30. Chem Biodivers. 2023. PMID: 37994208
Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma.
McCrury M, Swafford K, Shuttleworth SL, Mehdi SH, Acharya B, Saha D, Naceanceno K, Byrum SD, Storey AJ, Xu YZ, Doshier C, Patel V, Post GR, De Loose A, Rodriguez A, Shultz LD, Zhan F, Yoon D, Frett B, Kendrick S. McCrury M, et al. Among authors: de loose a. Mol Cancer Ther. 2024 Mar 4;23(3):316-329. doi: 10.1158/1535-7163.MCT-23-0299. Mol Cancer Ther. 2024. PMID: 37816504