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Proliferation of cardiomyocytes: a question unresolved.
De Falco M, Cobellis G, De Luca A. De Falco M, et al. Front Biosci (Elite Ed). 2009 Jun 1;1:528-36. doi: 10.2741/e49. Front Biosci (Elite Ed). 2009. PMID: 19482667 Review.
In the past, human heart has been considered a post-mitotic organ formed by cells, like adult cardiomyocytes, terminally differentiated and incapable of proliferation. ...
In the past, human heart has been considered a post-mitotic organ formed by cells, like adult cardiomyocytes, terminally differentiat …
Coexpression of Helicobacter pylori's proteins CagA and HspB induces cell proliferation in AGS gastric epithelial cells, independently from the bacterial infection.
De Luca A, Baldi A, Russo P, Todisco A, Altucci L, Giardullo N, Pasquale L, Iaquinto S, D'Onofrio V, Parodi MC, Paggi MG, Iaquinto G. De Luca A, et al. Cancer Res. 2003 Oct 1;63(19):6350-6. Cancer Res. 2003. PMID: 14559823
The effects of these two proteins on cell kinetics and the ability to selectively affect the expression of cell cycle-related proteins by transfection of a human gastric epithelial cell line (AGS) were analyzed. ...All these data suggest that CagA and HspB, independently f …
The effects of these two proteins on cell kinetics and the ability to selectively affect the expression of cell cycle-related proteins by tr …
Helicobacter pylori and gastric diseases: a dangerous association.
De Luca A, Iaquinto G. De Luca A, et al. Cancer Lett. 2004 Sep 15;213(1):1-10. doi: 10.1016/j.canlet.2004.06.006. Cancer Lett. 2004. PMID: 15312678 Review.
The bacterium Helicobacter pylori is linked to the appearance of several gastric diseases and in particular is associated with a progression to gastric cancer. ...
The bacterium Helicobacter pylori is linked to the appearance of several gastric diseases and in particular is associated with a prog …
Down-regulation of aquaporin 4 in human placenta throughout pregnancy.
De Falco M, Cobellis L, Torella M, Acone G, Varano L, Sellitti A, Ragucci A, Coppola G, Cassandro R, Laforgia V, Varano L, De Luca A. De Falco M, et al. In Vivo. 2007 Sep-Oct;21(5):813-7. In Vivo. 2007. PMID: 18019416
BACKGROUND: The family of mammalian aquaporins (AQP) consists of 12 known members, each with a specific tissue distribution and membrane localization pattern. ...MATERIALS AND METHODS: A total of 30 samples, 15 full-term placentae and 15 chorionic villous samples fr …
BACKGROUND: The family of mammalian aquaporins (AQP) consists of 12 known members, each with a specific tissue distribution and membr …
Cell cycle as a target of antineoplastic drugs.
De Falco M, De Luca A. De Falco M, et al. Curr Pharm Des. 2010;16(12):1417-26. doi: 10.2174/138161210791033914. Curr Pharm Des. 2010. PMID: 20166983 Review.
The cell cycle consists of a number of complex biochemical pathways that ensure that the start of a particular event depends on the successful and right end of previous steps in the pathway. ...Starting from a description of cell cycle, this review summarizes …
The cell cycle consists of a number of complex biochemical pathways that ensure that the start of a particular event depends o …
Identification of protein-protein interactions of human HtrA1.
Campioni M, Severino A, Manente L, De Luca A, La Porta R, Vitiello A, Fiore P, Toldo S, Spugnini EP, Paggi MG, Baldi A. Campioni M, et al. Front Biosci (Elite Ed). 2011 Jun 1;3:1493-9. doi: 10.2741/e350. Front Biosci (Elite Ed). 2011. PMID: 21622153
The human heat shock protein HtrA1, a member of the HtrA family of serine proteases, is a evolutionarily highly conserved factor which displays a widespread pattern of expression. ...These putative binding partners of HtrA1 appeared to be a) components …
The human heat shock protein HtrA1, a member of the HtrA family of serine proteases, is a evolutionarily highly conserved fact …
Localization and distribution of wolframin in human tissues.
De Falco M, Manente L, Lucariello A, Baldi G, Fiore P, Laforgia V, Baldi A, Iannaccone A, De Luca A. De Falco M, et al. Front Biosci (Elite Ed). 2012 Jan 1;4:1986-98. doi: 10.2741/519. Front Biosci (Elite Ed). 2012. PMID: 22202014
Wolframin is a transmembrane glycoprotein of 890 aminoacids, encoded by WFS1 gene. WFS1 mutations are responsible for Wolfram syndrome, an autosomal recessive disorder. ...In adult human tissues a variable positive staining was observed in both simple and stratified …
Wolframin is a transmembrane glycoprotein of 890 aminoacids, encoded by WFS1 gene. WFS1 mutations are responsible for Wolfram syndrom …
Small leucine rich proteoglycans are differently distributed in normal and pathological endometrium.
Lucariello A, Trabucco E, Boccia O, Perna A, Sellitto C, Castaldi MA, De Falco M, De Luca A, Cobellis L. Lucariello A, et al. In Vivo. 2015 Mar-Apr;29(2):217-22. In Vivo. 2015. PMID: 25792648
We observed an increase of lumican from proliferative to secretory phase of the endometrium and a decrease of fibromodulin, biglycan and decorin. ...
We observed an increase of lumican from proliferative to secretory phase of the endometrium and a decrease of fibromodulin, biglycan …
Different Impact Of Antiretroviral Drugs On Bone Differentiation In An In Vitro Model.
Esposito V, Perna A, Lucariello A, Carleo MA, Viglietti R, Sangiovanni V, Coppola N, Guerra G, De Luca A, Chirianni A. Esposito V, et al. J Cell Biochem. 2015 Oct;116(10):2188-94. doi: 10.1002/jcb.25169. J Cell Biochem. 2015. PMID: 25808410
According to our observation, treatment with TDF and ABC affects the ability of the cells to produce calcium deposits with a reduced expression of type I collagen gene and p21 mRNA, also increasing the activity of Wnt3a related pathway. ...DRV and EFV partially affect coll …
According to our observation, treatment with TDF and ABC affects the ability of the cells to produce calcium deposits with a reduced …
Differential expression of several factors involved in placental development in normal and abnormal condition.
Hay E, Lucariello A, Contieri M, Trucillo M, Pavese L, Guerra G, De Falco M, De Luca A, Perna A. Hay E, et al. Placenta. 2020 Jun;95:1-8. doi: 10.1016/j.placenta.2020.04.006. Epub 2020 Apr 20. Placenta. 2020. PMID: 32339142
The placenta, a temporary organ that forms during pregnancy, is the largest fetal organ and the first to develop. It is recognized as an organ that plays a vital role as a metabolic and physical barrier in the fetoplacental unit; throughout fetal development …
The placenta, a temporary organ that forms during pregnancy, is the largest fetal organ and the first to develop. It is recognized as …
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