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Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies.
Poppe B, Vandesompele J, Schoch C, Lindvall C, Mrozek K, Bloomfield CD, Beverloo HB, Michaux L, Dastugue N, Herens C, Yigit N, De Paepe A, Hagemeijer A, Speleman F. Poppe B, et al. Among authors: de paepe a. Blood. 2004 Jan 1;103(1):229-35. doi: 10.1182/blood-2003-06-2163. Epub 2003 Aug 28. Blood. 2004. PMID: 12946992 Free article.
EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22.
De Weer A, Speleman F, Cauwelier B, Van Roy N, Yigit N, Verhasselt B, De Moerloose B, Benoit Y, Noens L, Selleslag D, Lippert E, Struski S, Bastard C, De Paepe A, Vandenberghe P, Hagemeijer A, Dastugue N, Poppe B; Groupe Français de Cytogénétique Hématologique (GFCH). De Weer A, et al. Among authors: de moerloose b, de paepe a. Haematologica. 2008 Dec;93(12):1903-7. doi: 10.3324/haematol.13192. Epub 2008 Sep 24. Haematologica. 2008. PMID: 18815193 Free article.
PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements.
Poppe B, De Paepe P, Michaux L, Dastugue N, Bastard C, Herens C, Moreau E, Cavazzini F, Yigit N, Van Limbergen H, De Paepe A, Praet M, De Wolf-Peeters C, Wlodarska I, Speleman F. Poppe B, et al. Among authors: de paepe a, de paepe p, de wolf peeters c. Genes Chromosomes Cancer. 2005 Oct;44(2):218-23. doi: 10.1002/gcc.20214. Genes Chromosomes Cancer. 2005. PMID: 15942942
HOXA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS.
Poppe B, Yigit N, De Moerloose B, De Paepe A, Benoit Y, Speleman F. Poppe B, et al. Among authors: de moerloose b, de paepe a. Cancer Genet Cytogenet. 2005 Oct 1;162(1):82-4. doi: 10.1016/j.cancergencyto.2005.03.004. Cancer Genet Cytogenet. 2005. PMID: 16157206
497 results