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Parental imprinting of the mouse insulin-like growth factor II gene.
DeChiara TM, Robertson EJ, Efstratiadis A. DeChiara TM, et al. Cell. 1991 Feb 22;64(4):849-59. doi: 10.1016/0092-8674(91)90513-x. Cell. 1991. PMID: 1997210
Requirement of FGF-4 for postimplantation mouse development.
Feldman B, Poueymirou W, Papaioannou VE, DeChiara TM, Goldfarb M. Feldman B, et al. Among authors: dechiara tm. Science. 1995 Jan 13;267(5195):246-9. doi: 10.1126/science.7809630. Science. 1995. PMID: 7809630
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting.
DeChiara TM, Efstratiadis A, Robertson EJ. DeChiara TM, et al. Nature. 1990 May 3;345(6270):78-80. doi: 10.1038/345078a0. Nature. 1990. PMID: 2330056
Agrin acts via a MuSK receptor complex.
Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, Ryan TE, Gies DR, Shah S, Mattsson K, Burden SJ, DiStefano PS, Valenzuela DM, DeChiara TM, Yancopoulos GD. Glass DJ, et al. Among authors: dechiara tm. Cell. 1996 May 17;85(4):513-23. doi: 10.1016/s0092-8674(00)81252-0. Cell. 1996. PMID: 8653787
The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo.
DeChiara TM, Bowen DC, Valenzuela DM, Simmons MV, Poueymirou WT, Thomas S, Kinetz E, Compton DL, Rojas E, Park JS, Smith C, DiStefano PS, Glass DJ, Burden SJ, Yancopoulos GD. DeChiara TM, et al. Cell. 1996 May 17;85(4):501-12. doi: 10.1016/s0092-8674(00)81251-9. Cell. 1996. PMID: 8653786
Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth.
DeChiara TM, Vejsada R, Poueymirou WT, Acheson A, Suri C, Conover JC, Friedman B, McClain J, Pan L, Stahl N, Ip NY, Yancopoulos GD. DeChiara TM, et al. Cell. 1995 Oct 20;83(2):313-22. doi: 10.1016/0092-8674(95)90172-8. Cell. 1995. PMID: 7585948
A promoter of the rat insulin-like growth factor II gene consists of minimal control elements.
Evans T, DeChiara T, Efstratiadis A. Evans T, et al. J Mol Biol. 1988 Jan 5;199(1):61-81. doi: 10.1016/0022-2836(88)90379-8. J Mol Biol. 1988. PMID: 3351924
F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.
Poueymirou WT, Auerbach W, Frendewey D, Hickey JF, Escaravage JM, Esau L, Doré AT, Stevens S, Adams NC, Dominguez MG, Gale NW, Yancopoulos GD, DeChiara TM, Valenzuela DM. Poueymirou WT, et al. Among authors: dechiara tm. Nat Biotechnol. 2007 Jan;25(1):91-9. doi: 10.1038/nbt1263. Epub 2006 Dec 24. Nat Biotechnol. 2007. PMID: 17187059
Motoneuron survival is enhanced in the absence of neuromuscular junction formation in embryos.
Terrado J, Burgess RW, DeChiara T, Yancopoulos G, Sanes JR, Kato AC. Terrado J, et al. J Neurosci. 2001 May 1;21(9):3144-50. doi: 10.1523/JNEUROSCI.21-09-03144.2001. J Neurosci. 2001. PMID: 11312299 Free PMC article.
Producing fully ES cell-derived mice from eight-cell stage embryo injections.
DeChiara TM, Poueymirou WT, Auerbach W, Frendewey D, Yancopoulos GD, Valenzuela DM. DeChiara TM, et al. Methods Enzymol. 2010;476:285-94. doi: 10.1016/S0076-6879(10)76016-X. Methods Enzymol. 2010. PMID: 20691872
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