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Page 1
The genetic architecture of type 2 diabetes.
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Tajes JF, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SCJ, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MCY, Palmer ND, Balkau B, Stančáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JMM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VKL, Park KS, Saleheen D, So WY, Tam CHT, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler… See abstract for full author list ➔ Fuchsberger C, et al. Among authors: defronzo ra. Nature. 2016 Aug 4;536(7614):41-47. doi: 10.1038/nature18642. Epub 2016 Jul 11. Nature. 2016. PMID: 27398621 Free PMC article.
Further evidence for a type 2 diabetes susceptibility locus on chromosome 11q.
Duggirala R, Almasy L, Blangero J, Jenkinson CP, Arya R, DeFronzo RA, Stern MP, O'Connell P; American Diabetes Association GENNID Study Group. Duggirala R, et al. Among authors: defronzo ra. Genet Epidemiol. 2003 Apr;24(3):240-2. doi: 10.1002/gepi.10233. Genet Epidemiol. 2003. PMID: 12652528 No abstract available.
Lipid infusion decreases the expression of nuclear encoded mitochondrial genes and increases the expression of extracellular matrix genes in human skeletal muscle.
Richardson DK, Kashyap S, Bajaj M, Cusi K, Mandarino SJ, Finlayson J, DeFronzo RA, Jenkinson CP, Mandarino LJ. Richardson DK, et al. Among authors: defronzo ra. J Biol Chem. 2005 Mar 18;280(11):10290-7. doi: 10.1074/jbc.M408985200. Epub 2004 Dec 14. J Biol Chem. 2005. PMID: 15598661 Free article.
A quantitative trait locus (QTL) on chromosome 6q influences birth weight in two independent family studies.
Arya R, Demerath E, Jenkinson CP, Göring HH, Puppala S, Farook V, Fowler S, Schneider J, Granato R, Resendez RG, Dyer TD, Cole SA, Almasy L, Comuzzie AG, Siervogel RM, Bradshaw B, DeFronzo RA, MacCluer J, Stern MP, Towne B, Blangero J, Duggirala R. Arya R, et al. Among authors: defronzo ra. Hum Mol Genet. 2006 May 15;15(10):1569-79. doi: 10.1093/hmg/ddl076. Epub 2006 Apr 12. Hum Mol Genet. 2006. PMID: 16611675
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study.
Sriwijitkamol A, Coletta DK, Wajcberg E, Balbontin GB, Reyna SM, Barrientes J, Eagan PA, Jenkinson CP, Cersosimo E, DeFronzo RA, Sakamoto K, Musi N. Sriwijitkamol A, et al. Among authors: defronzo ra. Diabetes. 2007 Mar;56(3):836-48. doi: 10.2337/db06-1119. Diabetes. 2007. PMID: 17327455 Free PMC article. Clinical Trial.
Association of genetic variation in ENPP1 with obesity-related phenotypes.
Jenkinson CP, Coletta DK, Flechtner-Mors M, Hu SL, Fourcaudot MJ, Rodriguez LM, Schneider J, Arya R, Stern MP, Blangero J, Duggirala R, DeFronzo RA. Jenkinson CP, et al. Among authors: defronzo ra. Obesity (Silver Spring). 2008 Jul;16(7):1708-13. doi: 10.1038/oby.2008.262. Epub 2008 May 8. Obesity (Silver Spring). 2008. PMID: 18464750 Free PMC article.
669 results