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Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.
Panagopoulos V, Zinonos I, Leach DA, Hay SJ, Liapis V, Zysk A, Ingman WV, DeNichilo MO, Evdokiou A. Panagopoulos V, et al. Among authors: denichilo mo. Int J Biochem Cell Biol. 2015 Nov;68:128-38. doi: 10.1016/j.biocel.2015.09.006. Epub 2015 Sep 18. Int J Biochem Cell Biol. 2015. PMID: 26386352
Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma.
Liapis V, Zysk A, DeNichilo M, Zinonos I, Hay S, Panagopoulos V, Shoubridge A, Difelice C, Ponomarev V, Ingman W, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A. Liapis V, et al. Cancer Med. 2017 Sep;6(9):2164-2176. doi: 10.1002/cam4.1115. Epub 2017 Aug 10. Cancer Med. 2017. PMID: 28799237 Free PMC article.
Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer.
Zinonos I, Luo KW, Labrinidis A, Liapis V, Hay S, Panagopoulos V, Denichilo M, Ko CH, Yue GG, Lau CB, Ingman W, Ponomarev V, Atkins GJ, Findlay DM, Zannettino AC, Evdokiou A. Zinonos I, et al. Int J Oncol. 2014 Aug;45(2):532-40. doi: 10.3892/ijo.2014.2468. Epub 2014 May 27. Int J Oncol. 2014. PMID: 24865346 Free PMC article.
Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.
Panagopoulos V, Liapis V, Zinonos I, Hay S, Leach DA, Ingman W, DeNichilo MO, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A. Panagopoulos V, et al. Among authors: denichilo mo. Mol Cell Endocrinol. 2017 Jan 15;440:8-15. doi: 10.1016/j.mce.2016.11.007. Epub 2016 Nov 9. Mol Cell Endocrinol. 2017. PMID: 27836774
25 results