DePinho RA - Search Results

1

Artandi SE, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Carcinogenesis. 2010 Jan;31(1):9-18. doi: 10.1093/carcin/bgp268. Epub 2009 Nov 3. Carcinogenesis. 2010. PMID: 19887512 Free PMC article. Review.

2

A critical role for telomeres in suppressing and facilitating carcinogenesis.

Artandi SE, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Curr Opin Genet Dev. 2000 Feb;10(1):39-46. doi: 10.1016/s0959-437x(99)00047-7. Curr Opin Genet Dev. 2000. PMID: 10679392 Review.

3

Constitutive telomerase expression promotes mammary carcinomas in aging mice.

Artandi SE, Alson S, Tietze MK, Sharpless NE, Ye S, Greenberg RA, Castrillon DH, Horner JW, Weiler SR, Carrasco RD, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8191-6. doi: 10.1073/pnas.112515399. Epub 2002 May 28. Proc Natl Acad Sci U S A. 2002. PMID: 12034875 Free PMC article.

4

DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.

Maser RS, Wong KK, Sahin E, Xia H, Naylor M, Hedberg HM, Artandi SE, DePinho RA. Maser RS, et al. Among authors: depinho ra. Mol Cell Biol. 2007 Mar;27(6):2253-65. doi: 10.1128/MCB.01354-06. Epub 2006 Dec 4. Mol Cell Biol. 2007. PMID: 17145779 Free PMC article.

5

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.

Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA. Chin L, et al. Among authors: depinho ra. Cell. 1999 May 14;97(4):527-38. doi: 10.1016/s0092-8674(00)80762-x. Cell. 1999. PMID: 10338216 Free article.

6

Mice without telomerase: what can they teach us about human cancer?

Artandi SE, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Nat Med. 2000 Aug;6(8):852-5. doi: 10.1038/78595. Nat Med. 2000. PMID: 10932211 Review.

7

Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

O'Hagan RC, Chang S, Maser RS, Mohan R, Artandi SE, Chin L, DePinho RA. O'Hagan RC, et al. Among authors: depinho ra. Cancer Cell. 2002 Aug;2(2):149-55. doi: 10.1016/s1535-6108(02)00094-6. Cancer Cell. 2002. PMID: 12204535 Free article.

8

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.

Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Nature. 2000 Aug 10;406(6796):641-5. doi: 10.1038/35020592. Nature. 2000. PMID: 10949306

9

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.

Wong KK, Chang S, Weiler SR, Ganesan S, Chaudhuri J, Zhu C, Artandi SE, Rudolph KL, Gottlieb GJ, Chin L, Alt FW, DePinho RA. Wong KK, et al. Among authors: depinho ra. Nat Genet. 2000 Sep;26(1):85-8. doi: 10.1038/79232. Nat Genet. 2000. PMID: 10973255

10

Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer.

Perera SA, Maser RS, Xia H, McNamara K, Protopopov A, Chen L, Hezel AF, Kim CF, Bronson RT, Castrillon DH, Chin L, Bardeesy N, Depinho RA, Wong KK. Perera SA, et al. Among authors: depinho ra. Carcinogenesis. 2008 Apr;29(4):747-53. doi: 10.1093/carcin/bgn050. Epub 2008 Feb 17. Carcinogenesis. 2008. PMID: 18283039

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