DePinho RA - Search Results

1

Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.

Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G. Ferron M, et al. Among authors: depinho ra. Cell. 2010 Jul 23;142(2):296-308. doi: 10.1016/j.cell.2010.06.003. Cell. 2010. PMID: 20655470 Free PMC article.

2

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

Matsumoto M, Pocai A, Rossetti L, Depinho RA, Accili D. Matsumoto M, et al. Among authors: depinho ra. Cell Metab. 2007 Sep;6(3):208-16. doi: 10.1016/j.cmet.2007.08.006. Cell Metab. 2007. PMID: 17767907 Free article.

3

FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice.

Rached MT, Kode A, Silva BC, Jung DY, Gray S, Ong H, Paik JH, DePinho RA, Kim JK, Karsenty G, Kousteni S. Rached MT, et al. Among authors: depinho ra. J Clin Invest. 2010 Jan;120(1):357-68. doi: 10.1172/JCI39901. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038793 Free PMC article.

4

FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts.

Rached MT, Kode A, Xu L, Yoshikawa Y, Paik JH, Depinho RA, Kousteni S. Rached MT, et al. Among authors: depinho ra. Cell Metab. 2010 Feb 3;11(2):147-60. doi: 10.1016/j.cmet.2010.01.001. Cell Metab. 2010. PMID: 20142102 Free PMC article.

5

FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis.

Tsuchiya K, Tanaka J, Shuiqing Y, Welch CL, DePinho RA, Tabas I, Tall AR, Goldberg IJ, Accili D. Tsuchiya K, et al. Among authors: depinho ra. Cell Metab. 2012 Mar 7;15(3):372-81. doi: 10.1016/j.cmet.2012.01.018. Cell Metab. 2012. PMID: 22405072 Free PMC article.

6

Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1.

Kajimura D, Lee HW, Riley KJ, Arteaga-Solis E, Ferron M, Zhou B, Clarke CJ, Hannun YA, DePinho RA, Guo XE, Mann JJ, Karsenty G. Kajimura D, et al. Among authors: depinho ra. Cell Metab. 2013 Jun 4;17(6):901-915. doi: 10.1016/j.cmet.2013.04.009. Epub 2013 May 16. Cell Metab. 2013. PMID: 23684624 Free PMC article.

7

A genetic screen for candidate tumor suppressors identifies REST.

Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. Westbrook TF, et al. Among authors: depinho ra. Cell. 2005 Jun 17;121(6):837-48. doi: 10.1016/j.cell.2005.03.033. Cell. 2005. PMID: 15960972 Free article.

8

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, DePinho RA, Gilliland DG. Tothova Z, et al. Among authors: depinho ra. Cell. 2007 Jan 26;128(2):325-39. doi: 10.1016/j.cell.2007.01.003. Cell. 2007. PMID: 17254970 Free article.

9

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.

Dong XC, Copps KD, Guo S, Li Y, Kollipara R, DePinho RA, White MF. Dong XC, et al. Among authors: depinho ra. Cell Metab. 2008 Jul;8(1):65-76. doi: 10.1016/j.cmet.2008.06.006. Cell Metab. 2008. PMID: 18590693 Free PMC article.

10

PI3 kinase signals BCR-dependent mature B cell survival.

Srinivasan L, Sasaki Y, Calado DP, Zhang B, Paik JH, DePinho RA, Kutok JL, Kearney JF, Otipoby KL, Rajewsky K. Srinivasan L, et al. Among authors: depinho ra. Cell. 2009 Oct 30;139(3):573-86. doi: 10.1016/j.cell.2009.08.041. Cell. 2009. PMID: 19879843 Free PMC article.

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