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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.
Morgenbesser SD, Williams BO, Jacks T, DePinho RA. Morgenbesser SD, et al. Nature. 1994 Sep 1;371(6492):72-4. doi: 10.1038/371072a0. Nature. 1994. PMID: 8072529
Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivo.
Gómez Lahoz E, Liegeois NJ, Zhang P, Engelman JA, Horner J, Silverman A, Burde R, Roussel MF, Sherr CJ, Elledge SJ, DePinho RA. Gómez Lahoz E, et al. Mol Cell Biol. 1999 Jan;19(1):353-63. doi: 10.1128/mcb.19.1.353. Mol Cell Biol. 1999. PMID: 9858559 Free PMC article.
Essential role of mouse telomerase in highly proliferative organs.
Lee HW, Blasco MA, Gottlieb GJ, Horner JW 2nd, Greider CW, DePinho RA. Lee HW, et al. Nature. 1998 Apr 9;392(6676):569-74. doi: 10.1038/33345. Nature. 1998. PMID: 9560153
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53.
Pomerantz J, Schreiber-Agus N, Liégeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA. Pomerantz J, et al. Cell. 1998 Mar 20;92(6):713-23. doi: 10.1016/s0092-8674(00)81400-2. Cell. 1998. PMID: 9529248
Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.
Chin L, Pomerantz J, Polsky D, Jacobson M, Cohen C, Cordon-Cardo C, Horner JW 2nd, DePinho RA. Chin L, et al. Genes Dev. 1997 Nov 1;11(21):2822-34. doi: 10.1101/gad.11.21.2822. Genes Dev. 1997. PMID: 9353252 Free PMC article.
Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression.
Alland L, Muhle R, Hou H Jr, Potes J, Chin L, Schreiber-Agus N, DePinho RA. Alland L, et al. Nature. 1997 May 1;387(6628):49-55. doi: 10.1038/387049a0. Nature. 1997. PMID: 9139821
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