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Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells.
Min SY, Desai A, Yang Z, Sharma A, DeSouza T, Genga RMJ, Kucukural A, Lifshitz LM, Nielsen S, Scheele C, Maehr R, Garber M, Corvera S. Min SY, et al. Among authors: desouza t. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17970-17979. doi: 10.1073/pnas.1906512116. Epub 2019 Aug 16. Proc Natl Acad Sci U S A. 2019. PMID: 31420514 Free PMC article.
Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells.
Rojas-Rodriguez R, Lujan-Hernandez J, Min SY, DeSouza T, Teebagy P, Desai A, Tessier H, Slamin R, Siegel-Reamer L, Berg C, Baez A, Lalikos J, Corvera S. Rojas-Rodriguez R, et al. Among authors: desouza t. Tissue Eng Part A. 2019 Jun;25(11-12):842-854. doi: 10.1089/ten.TEA.2018.0067. Epub 2019 Jan 4. Tissue Eng Part A. 2019. PMID: 30306830 Free PMC article.
Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473.
Tran KV, Brown EL, DeSouza T, Jespersen NZ, Nandrup-Bus C, Yang Q, Yang Z, Desai A, Min SY, Rojas-Rodriguez R, Lundh M, Feizi A, Willenbrock H, Larsen TJ, Severinsen MCK, Malka K, Mozzicato AM, Deshmukh AS, Emanuelli B, Pedersen BK, Fitzgibbons T, Scheele C, Corvera S, Nielsen S. Tran KV, et al. Among authors: desouza t. Nat Metab. 2020 May;2(5):397-412. doi: 10.1038/s42255-020-0205-x. Epub 2020 May 21. Nat Metab. 2020. PMID: 32440655 Free PMC article.
PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans.
Rojas-Rodriguez R, Ziegler R, DeSouza T, Majid S, Madore AS, Amir N, Pace VA, Nachreiner D, Alfego D, Mathew J, Leung K, Moore Simas TA, Corvera S. Rojas-Rodriguez R, et al. Among authors: desouza t. Sci Transl Med. 2020 Nov 25;12(571):eaay4145. doi: 10.1126/scitranslmed.aay4145. Sci Transl Med. 2020. PMID: 33239385 Free PMC article.
CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease.
Tsagkaraki E, Nicoloro SM, DeSouza T, Solivan-Rivera J, Desai A, Lifshitz LM, Shen Y, Kelly M, Guilherme A, Henriques F, Amrani N, Ibraheim R, Rodriguez TC, Luk K, Maitland S, Friedline RH, Tauer L, Hu X, Kim JK, Wolfe SA, Sontheimer EJ, Corvera S, Czech MP. Tsagkaraki E, et al. Among authors: desouza t. Nat Commun. 2021 Nov 26;12(1):6931. doi: 10.1038/s41467-021-27190-y. Nat Commun. 2021. PMID: 34836963 Free PMC article.
Wnt signaling preserves progenitor cell multipotency during adipose tissue development.
Yang Loureiro Z, Joyce S, DeSouza T, Solivan-Rivera J, Desai A, Skritakis P, Yang Q, Ziegler R, Zhong D, Nguyen TT, MacDougald OA, Corvera S. Yang Loureiro Z, et al. Among authors: desouza t. Nat Metab. 2023 Jun;5(6):1014-1028. doi: 10.1038/s42255-023-00813-y. Epub 2023 Jun 19. Nat Metab. 2023. PMID: 37337125 Free PMC article.
The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekofer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LeBoeuf NR, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM. Townsend EC, et al. Among authors: desouza ta. Cancer Cell. 2016 Apr 11;29(4):574-586. doi: 10.1016/j.ccell.2016.03.008. Cancer Cell. 2016. PMID: 27070704 Free PMC article.
31 results