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Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors.
Yeh BJ, Rutigliano RJ, Deb A, Bar-Sagi D, Lim WA. Yeh BJ, et al. Among authors: deb a. Nature. 2007 May 31;447(7144):596-600. doi: 10.1038/nature05851. Epub 2007 May 21. Nature. 2007. PMID: 17515921
There are over 80 Rho GEFs in the human genome (compared to only 22 genes for the Rho GTPases themselves), and the evolution of new and diverse GEFs is thought to provide a mechanism for linking the core cytoskeletal machinery to a wide range of new control inputs. …
There are over 80 Rho GEFs in the human genome (compared to only 22 genes for the Rho GTPases themselves), and the evolution of new and dive …
Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.
Deb A, Zamanian-Daryoush M, Xu Z, Kadereit S, Williams BR. Deb A, et al. EMBO J. 2001 May 15;20(10):2487-96. doi: 10.1093/emboj/20.10.2487. EMBO J. 2001. PMID: 11350938 Free PMC article.
Taken together, these results establish PKR as an upstream regulator of activation of Stat3 and as a common mediator of both growth-promoting and growth-inhibitory signals....
Taken together, these results establish PKR as an upstream regulator of activation of Stat3 and as a common mediator of both growth-p …
RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway.
Deb A, Haque SJ, Mogensen T, Silverman RH, Williams BR. Deb A, et al. J Immunol. 2001 May 15;166(10):6170-80. doi: 10.4049/jimmunol.166.10.6170. J Immunol. 2001. PMID: 11342638
It also acts as a signal transducer for transcription factors NF-kappaB, IFN regulatory factor-1, and activating transcription factor-2. IFN-gamma, a pleiotropic cytokine, elicits gene expression by activating the Janus kinase-STAT signaling pathway. IFN-gamma can s …
It also acts as a signal transducer for transcription factors NF-kappaB, IFN regulatory factor-1, and activating transcription factor …
Roles of protein-tyrosine phosphatases in Stat1 alpha-mediated cell signaling.
Haque SJ, Flati V, Deb A, Williams BR. Haque SJ, et al. Among authors: deb a. J Biol Chem. 1995 Oct 27;270(43):25709-14. doi: 10.1074/jbc.270.43.25709. J Biol Chem. 1995. PMID: 7592750
A 4-6-h exposure of the permeabilized cells to orthovanadate, molybdate, and tungstate, but not vanadyl sulfate, results in a ligand-independent activation of Stat1 alpha, which is blocked by the inhibition or depletion of NADPH oxidase activity in the cells, indica
A 4-6-h exposure of the permeabilized cells to orthovanadate, molybdate, and tungstate, but not vanadyl sulfate, results in a
A 25-kDa beta-lactam-induced outer membrane protein of Vibrio cholerae. Purification and characterization.
Deb A, Bhattacharyya D, Das J. Deb A, et al. J Biol Chem. 1995 Feb 17;270(7):2914-20. doi: 10.1074/jbc.270.7.2914. J Biol Chem. 1995. PMID: 7852369
It is a basic (pI 8.5) protein rich in beta-sheet structure and is a homodimer, the monomers being held together by hydrophobic interactions. ...The protein does not have beta-lactamase or autolytic activity and is not a penicillin-binding protein. The Stoke' …
It is a basic (pI 8.5) protein rich in beta-sheet structure and is a homodimer, the monomers being held together by hydrophobi …
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB.
Kumar A, Yang YL, Flati V, Der S, Kadereit S, Deb A, Haque J, Reis L, Weissmann C, Williams BR. Kumar A, et al. Among authors: deb a. EMBO J. 1997 Jan 15;16(2):406-16. doi: 10.1093/emboj/16.2.406. EMBO J. 1997. PMID: 9029159 Free PMC article.
The lack of responsiveness could be attributed to a diminished activation of IRF-1 and/or NF-kappaB in response to IFN-gamma or pIC. Thus, PKR acts as a signal transducer for IFN-stimulated genes dependent on the transcription factors IRF-1 and NF-kappaB....
The lack of responsiveness could be attributed to a diminished activation of IRF-1 and/or NF-kappaB in response to IFN-gamma or pIC. …
Endophthalmitis due to Delftia acidovorans: An unusual ocular pathogen.
Deb AK, Chavhan P, Chowdhury SS, Sistla S, Sugumaran R, Panicker G. Deb AK, et al. Indian J Ophthalmol. 2020 Nov;68(11):2591-2594. doi: 10.4103/ijo.IJO_373_20. Indian J Ophthalmol. 2020. PMID: 33120704
LncRBase V.2: an updated resource for multispecies lncRNAs and ClinicLSNP hosting genetic variants in lncRNAs for cancer patients.
Das T, Deb A, Parida S, Mondal S, Khatua S, Ghosh Z. Das T, et al. Among authors: deb a. RNA Biol. 2020 Oct 28:1-16. doi: 10.1080/15476286.2020.1833529. Online ahead of print. RNA Biol. 2020. PMID: 33112702
Exosomes: A new horizon in modern medicine.
Deb A, Gupta S, Mazumder PB. Deb A, et al. Life Sci. 2020 Oct 20:118623. doi: 10.1016/j.lfs.2020.118623. Online ahead of print. Life Sci. 2020. PMID: 33096118 Review.
Role of Exercise in Blood Pressure Control Among Hypertensive Chronic Kidney Disease Patients.
Okechukwu CE, Deb A. Okechukwu CE, et al. Among authors: deb a. Int J Prev Med. 2020 Sep 5;11:142. doi: 10.4103/ijpvm.IJPVM_252_19. eCollection 2020. Int J Prev Med. 2020. PMID: 33088470 Free PMC article. No abstract available.
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