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1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity.
Witvrouw M, Arranz ME, Pannecouque C, Declercq R, Jonckheere H, Schmit JC, Vandamme AM, Diaz JA, Ingate ST, Desmyter J, Esnouf R, Van Meervelt L, Vega S, Balzarini J, De Clercq E. Witvrouw M, et al. Among authors: declercq r. Antimicrob Agents Chemother. 1998 Mar;42(3):618-23. doi: 10.1128/AAC.42.3.618. Antimicrob Agents Chemother. 1998. PMID: 9517942 Free PMC article.
The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
Li W, Wang Y, Lohith TG, Zeng Z, Tong L, Mazzola R, Riffel K, Miller P, Purcell M, Holahan M, Haley H, Gantert L, Hesk D, Ren S, Morrow J, Uslaner J, Struyk A, Wai JM, Rudd MT, Tellers DM, McAvoy T, Bormans G, Koole M, Van Laere K, Serdons K, de Hoon J, Declercq R, De Lepeleire I, Pascual MB, Zanotti-Fregonara P, Yu M, Arbones V, Masdeu JC, Cheng A, Hussain A, Bueters T, Anderson MS, Hostetler ED, Basile AS. Li W, et al. Among authors: declercq r. Sci Transl Med. 2022 Jan 12;14(627):eabg3684. doi: 10.1126/scitranslmed.abg3684. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020407
Preclinical Safety Evaluation and Human Dosimetry of [18F]MK-6240, a Novel PET Tracer for Imaging Neurofibrillary Tangles.
Koole M, Lohith TG, Valentine JL, Bennacef I, Declercq R, Reynders T, Riffel K, Celen S, Serdons K, Bormans G, Ferry-Martin S, Laroque P, Walji A, Hostetler ED, Briscoe RJ, de Hoon J, Sur C, Van Laere K, Struyk A. Koole M, et al. Among authors: declercq r. Mol Imaging Biol. 2020 Feb;22(1):173-180. doi: 10.1007/s11307-019-01367-w. Mol Imaging Biol. 2020. PMID: 31111397
Hydrogen-Deuterium Exchange Supports Independent Membrane-Interfacial Fusion Peptide and Transmembrane Domains in Subunit 2 of Influenza Virus Hemagglutinin Protein, a Structured and Aqueous-Protected Connection between the Fusion Peptide and Soluble Ectodomain, and the Importance of Membrane Apposition by the Trimer-of-Hairpins Structure.
Ranaweera A, Ratnayake PU, Ekanayaka EAP, Declercq R, Weliky DP. Ranaweera A, et al. Among authors: declercq r. Biochemistry. 2019 May 14;58(19):2432-2446. doi: 10.1021/acs.biochem.8b01272. Epub 2019 May 1. Biochemistry. 2019. PMID: 31008587 Free PMC article.
Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles.
Lohith TG, Bennacef I, Vandenberghe R, Vandenbulcke M, Salinas CA, Declercq R, Reynders T, Telan-Choing NF, Riffel K, Celen S, Serdons K, Bormans G, Tsai K, Walji A, Hostetler ED, Evelhoch JL, Van Laere K, Forman M, Stoch A, Sur C, Struyk A. Lohith TG, et al. Among authors: declercq r. J Nucl Med. 2019 Jan;60(1):107-114. doi: 10.2967/jnumed.118.208215. Epub 2018 Jun 7. J Nucl Med. 2019. PMID: 29880509 Free article.
Quantification, Variability, and Reproducibility of Basal Skeletal Muscle Glucose Uptake in Healthy Humans Using 18F-FDG PET/CT.
Gheysens O, Postnov A, Deroose CM, Vandermeulen C, de Hoon J, Declercq R, Dennie J, Mixson L, De Lepeleire I, Van Laere K, Klimas M, Chakravarthy MV. Gheysens O, et al. Among authors: declercq r. J Nucl Med. 2015 Oct;56(10):1520-6. doi: 10.2967/jnumed.115.159715. Epub 2015 Jul 30. J Nucl Med. 2015. PMID: 26229142 Free article.
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