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Multidrug resistance associated with overexpression of MRP.
Cole SP, Deeley RG. Cole SP, et al. Cancer Treat Res. 1996;87:39-62. doi: 10.1007/978-1-4613-1267-3_2. Cancer Treat Res. 1996. PMID: 8886448 Review. No abstract available.
Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia.
Machiels JP, Govaerts AS, Guillaume T, Bayat B, Feyens AM, Lenoir E, Goeminne JC, Cole S, Deeley R, Caruso M, Bank A, Symann M, D'Hondt V. Machiels JP, et al. Hum Gene Ther. 1999 Mar 20;10(5):801-11. doi: 10.1089/10430349950018553. Hum Gene Ther. 1999. PMID: 10210147
Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function.
Qin L, Tam SP, Deeley RG. Qin L, et al. Among authors: deeley rg. Drug Metab Dispos. 2012 Jul;40(7):1403-13. doi: 10.1124/dmd.112.044867. Epub 2012 Apr 16. Drug Metab Dispos. 2012. PMID: 22511347
Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.
Conseil G, Deeley RG, Cole SP. Conseil G, et al. Pharmacogenet Genomics. 2005 Aug;15(8):523-33. doi: 10.1097/ Pharmacogenet Genomics. 2005. PMID: 16006996 Review.
Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).
Maeno K, Nakajima A, Conseil G, Rothnie A, Deeley RG, Cole SP. Maeno K, et al. Among authors: deeley rg. Drug Metab Dispos. 2009 Jul;37(7):1411-20. doi: 10.1124/dmd.109.026633. Epub 2009 Apr 27. Drug Metab Dispos. 2009. PMID: 19398503
Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
Conseil G, Rothnie AJ, Deeley RG, Cole SP. Conseil G, et al. Among authors: deeley rg. Mol Pharmacol. 2009 Feb;75(2):397-406. doi: 10.1124/mol.108.052860. Epub 2008 Nov 17. Mol Pharmacol. 2009. PMID: 19015228
Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).
Grant CE, Gao M, DeGorter MK, Cole SP, Deeley RG. Grant CE, et al. Among authors: deeley rg. Drug Metab Dispos. 2008 Dec;36(12):2571-81. doi: 10.1124/dmd.108.022491. Epub 2008 Sep 5. Drug Metab Dispos. 2008. PMID: 18775981
Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.
Rothnie A, Conseil G, Lau AY, Deeley RG, Cole SP. Rothnie A, et al. Among authors: deeley rg. Mol Pharmacol. 2008 Dec;74(6):1630-40. doi: 10.1124/mol.108.049080. Epub 2008 Sep 2. Mol Pharmacol. 2008. PMID: 18768387
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