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The good, the bad and the ugly - TFH cells in human health and disease.
Tangye SG, Ma CS, Brink R, Deenick EK. Tangye SG, et al. Among authors: deenick ek. Nat Rev Immunol. 2013 Jun;13(6):412-26. doi: 10.1038/nri3447. Epub 2013 May 17. Nat Rev Immunol. 2013. PMID: 23681096 Review.
Quantitative analysis of lymphocyte differentiation and proliferation in vitro using carboxyfluorescein diacetate succinimidyl ester.
Hasbold J, Gett AV, Rush JS, Deenick E, Avery D, Jun J, Hodgkin PD. Hasbold J, et al. Immunol Cell Biol. 1999 Dec;77(6):516-22. doi: 10.1046/j.1440-1711.1999.00874.x. Immunol Cell Biol. 1999. PMID: 10571672
Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses.
Tangye SG, Avery DT, Deenick EK, Hodgkin PD. Tangye SG, et al. Among authors: deenick ek. J Immunol. 2003 Jan 15;170(2):686-94. doi: 10.4049/jimmunol.170.2.686. J Immunol. 2003. PMID: 12517929
TCR affinity and negative regulation limit autoimmunity.
Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS. Gronski MA, et al. Among authors: deenick ek. Nat Med. 2004 Nov;10(11):1234-9. doi: 10.1038/nm1114. Epub 2004 Oct 3. Nat Med. 2004. PMID: 15467726
Autoimmunity: IL-21: a new player in Th17-cell differentiation.
Deenick EK, Tangye SG. Deenick EK, et al. Immunol Cell Biol. 2007 Oct;85(7):503-5. doi: 10.1038/sj.icb.7100114. Epub 2007 Sep 4. Immunol Cell Biol. 2007. PMID: 17768419 Review. No abstract available.
Immunology: Helpful T cells are sticky.
Deenick EK, Tangye SG. Deenick EK, et al. Nature. 2008 Oct 9;455(7214):745-7. doi: 10.1038/455745a. Nature. 2008. PMID: 18843357 No abstract available.
Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.
Ma CS, Suryani S, Avery DT, Chan A, Nanan R, Santner-Nanan B, Deenick EK, Tangye SG. Ma CS, et al. Among authors: deenick ek. Immunol Cell Biol. 2009 Nov-Dec;87(8):590-600. doi: 10.1038/icb.2009.64. Epub 2009 Sep 1. Immunol Cell Biol. 2009. PMID: 19721453
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.
Randall KL, Lambe T, Johnson AL, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, Deenick EK, Tangye SG, Chan TD, Camidge T, Brink R, Vinuesa CG, Batista FD, Cornall RJ, Goodnow CC. Randall KL, et al. Among authors: deenick ek. Nat Immunol. 2009 Dec;10(12):1283-91. doi: 10.1038/ni.1820. Epub 2009 Nov 8. Nat Immunol. 2009. PMID: 19898472 Free PMC article.
c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance.
Deenick EK, Po L, Chapatte L, Murakami K, Lu YC, Elford AR, Saibil SD, Ruland J, Gerondakis S, Mak TW, Ohashi PS. Deenick EK, et al. Eur J Immunol. 2010 Mar;40(3):867-77. doi: 10.1002/eji.200939445. Eur J Immunol. 2010. PMID: 19950170
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.
Avery DT, Deenick EK, Ma CS, Suryani S, Simpson N, Chew GY, Chan TD, Palendira U, Bustamante J, Boisson-Dupuis S, Choo S, Bleasel KE, Peake J, King C, French MA, Engelhard D, Al-Hajjar S, Al-Muhsen S, Magdorf K, Roesler J, Arkwright PD, Hissaria P, Riminton DS, Wong M, Brink R, Fulcher DA, Casanova JL, Cook MC, Tangye SG. Avery DT, et al. Among authors: deenick ek. J Exp Med. 2010 Jan 18;207(1):155-71. doi: 10.1084/jem.20091706. Epub 2010 Jan 4. J Exp Med. 2010. PMID: 20048285 Free PMC article.
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