Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.
Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T.
Kather JN, et al.
Nat Med. 2019 Jul;25(7):1054-1056. doi: 10.1038/s41591-019-0462-y. Epub 2019 Jun 3.
Nat Med. 2019.
PMID: 31160815
Free PMC article.
Microsatellite instability determines whether patients with gastrointestinal cancer respond exceptionally well to immunotherapy. However, in clinical practice, not every patient is tested for MSI, because this requires additional genetic or immunohisto …
Microsatellite instability determines whether patients with gastrointestinal cancer respond exceptionally well t …