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GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging.
Sekhar RV. Sekhar RV. J Nutr. 2021 Dec 3;151(12):3606-3616. doi: 10.1093/jn/nxab309. J Nutr. 2021. PMID: 34587244 Free article. Review.
Cellular increases in oxidative stress (OxS) and decline in mitochondrial function are identified as key defects in aging, but underlying mechanisms are poorly understood and interventions are lacking. ...Supplementation with GlyNAC (combination …
Cellular increases in oxidative stress (OxS) and decline in mitochondrial function are identified as key defects in aging …
Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation.
Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F. Sekhar RV, et al. Am J Clin Nutr. 2011 Sep;94(3):847-53. doi: 10.3945/ajcn.110.003483. Epub 2011 Jul 27. Am J Clin Nutr. 2011. PMID: 21795440 Free PMC article. Clinical Trial.
OBJECTIVE: We tested whether glutathione deficiency occurs because of diminished synthesis and contributes to oxidative stress in aging and whether stimulating glutathione synthesis with its precursors cysteine and …
OBJECTIVE: We tested whether glutathione deficiency occurs because of diminished synthesis and contributes to oxidat …