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Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.
Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L. Lin SJ, et al. Nature. 2002 Jul 18;418(6895):344-8. doi: 10.1038/nature00829. Nature. 2002. PMID: 12124627
Saccharomyces cerevisiae linker histone Hho1p functionally interacts with core histone H4 and negatively regulates the establishment of transcriptionally silent chromatin.
Yu Q, Kuzmiak H, Zou Y, Olsen L, Defossez PA, Bi X. Yu Q, et al. J Biol Chem. 2009 Jan 9;284(2):740-50. doi: 10.1074/jbc.M806274200. Epub 2008 Nov 18. J Biol Chem. 2009. PMID: 19017647 Free PMC article.
Sound silencing: the Sir2 protein and cellular senescence.
Defossez PA, Lin SJ, McNabb DS. Defossez PA, et al. Bioessays. 2001 Apr;23(4):327-32. doi: 10.1002/bies.1047. Bioessays. 2001. PMID: 11268038 Review.
Elimination of replication block protein Fob1 extends the life span of yeast mother cells.
Defossez PA, Prusty R, Kaeberlein M, Lin SJ, Ferrigno P, Silver PA, Keil RL, Guarente L. Defossez PA, et al. Mol Cell. 1999 Apr;3(4):447-55. doi: 10.1016/s1097-2765(00)80472-4. Mol Cell. 1999. PMID: 10230397
Vicious circles: a mechanism for yeast aging.
Defossez PA, Park PU, Guarente L. Defossez PA, et al. Curr Opin Microbiol. 1998 Dec;1(6):707-11. doi: 10.1016/s1369-5274(98)80119-7. Curr Opin Microbiol. 1998. PMID: 10066542 Review.
Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation.
Ferry L, Fournier A, Tsusaka T, Adelmant G, Shimazu T, Matano S, Kirsh O, Amouroux R, Dohmae N, Suzuki T, Filion GJ, Deng W, de Dieuleveult M, Fritsch L, Kudithipudi S, Jeltsch A, Leonhardt H, Hajkova P, Marto JA, Arita K, Shinkai Y, Defossez PA. Ferry L, et al. Among authors: defossez pa. Mol Cell. 2017 Aug 17;67(4):550-565.e5. doi: 10.1016/j.molcel.2017.07.012. Epub 2017 Aug 10. Mol Cell. 2017. PMID: 28803780 Free article.
The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso.
Defossez PA, Kelly KF, Filion GJ, PĂ©rez-Torrado R, Magdinier F, Menoni H, Nordgaard CL, Daniel JM, Gilson E. Defossez PA, et al. J Biol Chem. 2005 Dec 30;280(52):43017-23. doi: 10.1074/jbc.M510802200. Epub 2005 Oct 17. J Biol Chem. 2005. PMID: 16230345
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