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The following terms were not found in PubMed: kinetics+flavonoids+Flavonoids+high-performance, spectrometry+Intestinal, flora+Ziziphi
Page 1
Dynamic Metabolite Profile Changes in Semen Ziziphi Spinosae During Ripening.
Tian X, Zhang S, Gu L, Tian W, Liu L, Li Q, Jiang T. Tian X, et al. Rapid Commun Mass Spectrom. 2025 Apr 15;39(11):e10024. doi: 10.1002/rcm.10024. Rapid Commun Mass Spectrom. 2025. PMID: 40105258
RATIONALE: In traditional Chinese medicine, Semen Ziziphi Spinosae (SZS) is employed for alleviating conditions such as neurasthenia, sleep disorders, and anxiety. ...All the differential metabolites screened were enriched in 11 metabolic pathways, including glycero …
RATIONALE: In traditional Chinese medicine, Semen Ziziphi Spinosae (SZS) is employed for alleviating conditions such as neuras …
Systematically characterization of in vivo substances of Ziziphi Spinosae Semen in rats by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry analysis.
Li M, Zhang FX, Wei ZC, Li ZT, Zhang GX, Li HJ. Li M, et al. J Pharm Biomed Anal. 2021 Jan 30;193:113756. doi: 10.1016/j.jpba.2020.113756. Epub 2020 Nov 7. J Pharm Biomed Anal. 2021. PMID: 33217708
Ziziphi Spinosae Semen (ZSS), the seeds of Ziziphus jujuba var. spinosa, is widely used in China or other Asian countries for the treatment of insomnia and palpitation. In our previous work, chemical constituents in ZSS were profiled by ultra-high-performance …
Ziziphi Spinosae Semen (ZSS), the seeds of Ziziphus jujuba var. spinosa, is widely used in China or other Asian countri …
A UFLC-MS/MS method for simultaneous quantitation of spinosin, mangiferin and ferulic acid in rat plasma: application to a comparative pharmacokinetic study in normal and insomnic rats.
He B, Li Q, Jia Y, Zhao L, Xiao F, Lv C, Xu H, Chen X, Bi K. He B, et al. J Mass Spectrom. 2012 Oct;47(10):1333-40. doi: 10.1002/jms.3072. J Mass Spectrom. 2012. PMID: 23019165
Suan-Zao-Ren (SZR) decoction, consisting of Ziziphi Spinosae Semen, Poria, Chuanxiong Rhizoma, Anemarrhenae Rhizoma and Glycyrrhizae Radix Et Rhizoma, is a Traditional Chinese Medicine prescription, clinically used for the treatment of insomnia. ...
Suan-Zao-Ren (SZR) decoction, consisting of Ziziphi Spinosae Semen, Poria, Chuanxiong Rhizoma, Anemarrhenae Rhizoma and Glycyr …
Validation of an analytical method using UPLC-MS/MS to quantify four bioactive components in rat plasma and its application to pharmacokinetic study of traditional and dispensing granules decoction of Ziziphi Spinosae Semen.
Chen Y, Jiang E, Yan J, Tao Y. Chen Y, et al. Biomed Chromatogr. 2020 Apr;34(4):e4797. doi: 10.1002/bmc.4797. Epub 2020 Feb 8. Biomed Chromatogr. 2020. PMID: 31989669
A rapid and sensitive UPLC-MS/MS method was established for the simultaneous quantification of 6'''-feruloylspinosin, spinosin, jujuboside A, and jujuboside B in rat plasma after the oral administration of traditional and dispensing granules (DG) decoction of Ziziphi Spinosae …
A rapid and sensitive UPLC-MS/MS method was established for the simultaneous quantification of 6'''-feruloylspinosin, spinosin, jujuboside A …
Degradation Kinetics of 6-p-Coumaroylspinosin and Identification of Its Metabolites by Rat Intestinal Flora.
Jiao L, Li Y, Zhang Y, Liu J, Xie J, Zhang K, Zhou A. Jiao L, et al. J Agric Food Chem. 2017 Jun 7;65(22):4449-4455. doi: 10.1021/acs.jafc.7b01486. Epub 2017 May 25. J Agric Food Chem. 2017. PMID: 28513155
6-p-Coumaroylspinosin (P-CS), a bioactive flavonoid, is typically extracted from Semen Ziziphi Spinosae (SZS). In this study, a high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed to determine …
6-p-Coumaroylspinosin (P-CS), a bioactive flavonoid, is typically extracted from Semen Ziziphi Spinosae (SZS). In this study, …
Degradation kinetics of jujuboside b by rat intestinal flora in vitro with an RRLC-MS-MS method.
Zhang Y, Zhang Y, Zhang K, Ma G, Zhang M, Xie J. Zhang Y, et al. J Chromatogr Sci. 2014 Aug;52(7):691-6. doi: 10.1093/chromsci/bmt100. Epub 2013 Jul 4. J Chromatogr Sci. 2014. PMID: 23828910
Jujuboside B (JuB) is a main bioactive saponin constituent of Ziziphi Spinosae Semen, which is a traditional herb for the treatment of insomnia and anxiety. However, the detailed metabolic mechanism of JuB is poorly understood. In this study, a novel method of rapid …
Jujuboside B (JuB) is a main bioactive saponin constituent of Ziziphi Spinosae Semen, which is a traditional herb for the trea …
[Effective substance and mechanism of Ziziphi Spinosae Semen extract in treatment of insomnia based on serum metabolomics and network pharmacology].
Bian ZH, Zhang WM, Tang JY, Fei QQ, Hu MM, Chen XW, Su LL, Fei CH, Ji D, Mao CQ, Tong HJ, Lu TL, Yuan XH. Bian ZH, et al. Zhongguo Zhong Yao Za Zhi. 2022 Jan;47(1):188-202. doi: 10.19540/j.cnki.cjcmm.20210922.702. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 35178926 Chinese.
The potential biomarkers of the extract in the treatment of insomnia were screened by ultra-high performance liquid chromatography-mass spectrometry(UHPLC-MS) combined with multivariate analysis, and the related metabolic pathways were further analyzed. The & …
The potential biomarkers of the extract in the treatment of insomnia were screened by ultra-high performance liquid chromatography …
Determination of five neurotransmitters in the rat brain for the study of the hypnotic effects of Ziziphi Spinosae Semen aqueous extract on insomnia rat model by UPLC-MS/MS.
Yan Y, Li Q, DU HZ, Shen CX, Li AP, Pei XP, DU CH, Qin XM. Yan Y, et al. Chin J Nat Med. 2019 Jul;17(7):551-560. doi: 10.1016/S1875-5364(19)30077-9. Chin J Nat Med. 2019. PMID: 31514987
Ziziphi Spinosae Semen (ZSS) has been used for treatment of insomnia in China for centuries. To reveal the influence of insomnia on the levels of the neurotransmitters including serotonin (5-HT), glutamic acid (Glu), gamma-aminobutyric acid (GABA), noradrenaline (NE …
Ziziphi Spinosae Semen (ZSS) has been used for treatment of insomnia in China for centuries. To reveal the influence of insomn …
Identification of the absorptive constituents and their metabolites in vivo of Ziziphi Spinosae Semen by UPLC-ESI-Q-TOF-MS/MS.
Shang J, Chen XL, Li L, Zhang H, Yang L, Yang B, Cao L, Wang ZZ, Xiao W. Shang J, et al. Biomed Chromatogr. 2020 Dec;34(12):e4965. doi: 10.1002/bmc.4965. Epub 2020 Aug 24. Biomed Chromatogr. 2020. PMID: 32794231
In this research, ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS/MS) was used for detection and identification of the absorptive constituents and their metabolites in …
In this research, ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight ma …
[Determination of nine components of fried Ziziphi Spinosae Semen extract in beagle dog plasma by UPLC-MS/MS and its application in pharmacokinetic research].
Xia KX, Yu X, Wu SY, Zhao LF, Wang YY, Kang C, Yuan Z, Li YF. Xia KX, et al. Zhongguo Zhong Yao Za Zhi. 2024 May;49(9):2501-2511. doi: 10.19540/j.cnki.cjcmm.20240310.201. Zhongguo Zhong Yao Za Zhi. 2024. PMID: 38812154 Chinese.
This study established a convenient, rapid, and sensitive ultra-performance liquid chromatography tandem mass spectrometry(UPLC-MS/MS) method for simultaneous determination of magnoflorine,(R)-coclaurine, vicenin , isospinosin, spinosin, swertisin, N-n …
This study established a convenient, rapid, and sensitive ultra-performance liquid chromatography tandem mass sp …