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A Spatial Model of Insulin-Granule Dynamics in Pancreatic β-Cells.
Dehghany J, Hoboth P, Ivanova A, Mziaut H, Müller A, Kalaidzidis Y, Solimena M, Meyer-Hermann M. Dehghany J, et al. Traffic. 2015 Aug;16(8):797-813. doi: 10.1111/tra.12286. Epub 2015 May 1. Traffic. 2015. PMID: 25809669 Free article.
Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies.
Hoboth P, Müller A, Ivanova A, Mziaut H, Dehghany J, Sönmez A, Lachnit M, Meyer-Hermann M, Kalaidzidis Y, Solimena M. Hoboth P, et al. Among authors: dehghany j. Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E667-76. doi: 10.1073/pnas.1409542112. Epub 2015 Feb 2. Proc Natl Acad Sci U S A. 2015. PMID: 25646459 Free PMC article.
The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512.
Mziaut H, Mulligan B, Hoboth P, Otto O, Ivanova A, Herbig M, Schumann D, Hildebrandt T, Dehghany J, Sönmez A, Münster C, Meyer-Hermann M, Guck J, Kalaidzidis Y, Solimena M. Mziaut H, et al. Among authors: dehghany j. Mol Metab. 2016 Jun 10;5(8):656-668. doi: 10.1016/j.molmet.2016.05.015. eCollection 2016 Aug. Mol Metab. 2016. PMID: 27656403 Free PMC article.