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Development and validation of cell-based luciferase reporter gene assays for measuring neutralizing anti-drug antibodies against interferon beta.
Hermanrud C, Ryner M, Luft T, Jensen PE, Ingenhoven K, Rat D, Deisenhammer F, Sørensen PS, Pallardy M, Sikkema D, Bertotti E, Kramer D, Creeke P, Fogdell-Hahn A; ABIRISK Consortium. Hermanrud C, et al. Among authors: deisenhammer f. J Immunol Methods. 2016 Mar;430:1-9. doi: 10.1016/j.jim.2016.01.004. Epub 2016 Jan 11. J Immunol Methods. 2016. PMID: 26779831
Epitope specificity of neutralizing antibodies against IFN-beta.
Gneiss C, Reindl M, Berger T, Lutterotti A, Ehling R, Egg R, Deisenhammer F. Gneiss C, et al. Among authors: deisenhammer f. J Interferon Cytokine Res. 2004 May;24(5):283-90. doi: 10.1089/107999004323065066. J Interferon Cytokine Res. 2004. PMID: 15153311
Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis.
Sørensen PS, Deisenhammer F, Duda P, Hohlfeld R, Myhr KM, Palace J, Polman C, Pozzilli C, Ross C; EFNS Task Force on Anti-IFN-beta Antibodies in Multiple Sclerosis. Sørensen PS, et al. Among authors: deisenhammer f. Eur J Neurol. 2005 Nov;12(11):817-27. doi: 10.1111/j.1468-1331.2005.01386.x. Eur J Neurol. 2005. PMID: 16241970 Review.
Interferon-beta antibodies have a higher affinity in patients with neutralizing antibodies compared to patients with non-neutralizing antibodies.
Gneiss C, Tripp P, Ehling R, Khalil M, Lutterotti A, Egg R, Mayringer I, Künz B, Berger T, Reindl M, Deisenhammer F. Gneiss C, et al. Among authors: deisenhammer f. J Neuroimmunol. 2006 May;174(1-2):174-9. doi: 10.1016/j.jneuroim.2006.01.017. Epub 2006 Mar 23. J Neuroimmunol. 2006. PMID: 16556466 Clinical Trial.
251 results