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Recent developments in heterocycle labeling with carbon isotopes.
Del Vecchio A, Destro G, Taran F, Audisio D. Del Vecchio A, et al. J Labelled Comp Radiopharm. 2018 Nov;61(13):988-1007. doi: 10.1002/jlcr.3666. Epub 2018 Jul 13. J Labelled Comp Radiopharm. 2018. PMID: 29926506 Review.
Heterocycles play an essential role in modern pharmaceutical and agrochemical developments, representing a very common structural unit in marketed drugs. ...Their introduction into small organic molecules represents a crucial step for the radiochemists. Because the …
Heterocycles play an essential role in modern pharmaceutical and agrochemical developments, representing a very common structural uni …
Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2.
Del Vecchio A, Caillé F, Chevalier A, Loreau O, Horkka K, Halldin C, Schou M, Camus N, Kessler P, Kuhnast B, Taran F, Audisio D. Del Vecchio A, et al. Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9744-9748. doi: 10.1002/anie.201804838. Epub 2018 Jul 3. Angew Chem Int Ed Engl. 2018. PMID: 29862657 Free PMC article.
A robust, click-chemistry-inspired procedure for radiolabeling of cyclic ureas was developed. This protocol, suitable for all carbon isotopes ((11) C, (13) C, (14) C), is based on the direct functionalization of carbon dioxide: the universal building block for carbon radio
A robust, click-chemistry-inspired procedure for radiolabeling of cyclic ureas was developed. This protocol, suitable for all carbon
Transition-Metal-Free Carbon Isotope Exchange of Phenyl Acetic Acids.
Destro G, Horkka K, Loreau O, Buisson DA, Kingston L, Del Vecchio A, Schou M, Elmore CS, Taran F, Cantat T, Audisio D. Destro G, et al. Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13490-13495. doi: 10.1002/anie.202002341. Epub 2020 May 27. Angew Chem Int Ed Engl. 2020. PMID: 32348625
A transition-metal-free carbon isotope exchange procedure on phenyl acetic acids is described. Utilizing the universal precursor CO(2) , this protocol allows the carbon isotope to be inserted into the carboxylic acid position, with no need of precursor synthesis. ...A
A transition-metal-free carbon isotope exchange procedure on phenyl acetic acids is described. Utilizing the universal precursor CO(2
Deep Learning for Robust Decomposition of High-Density Surface EMG Signals.
Clarke AK, Atashzar SF, Del Vecchio A, Barsakcioglu DY, Muceli S, Bentley P, Urh F, Holobar A, Farina D. Clarke AK, et al. Among authors: del vecchio a. IEEE Trans Biomed Eng. 2020 Jul 2;PP. doi: 10.1109/TBME.2020.3006508. Online ahead of print. IEEE Trans Biomed Eng. 2020. PMID: 32746049
A novel rizatriptan oral gel formulation: Bioavailability and bioequivalence
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Tellone V, Dragone P, Picollo R, Rosignoli MT, Garofolo F, Del Vecchio A, Calisti F, Comandini A, Donath F, Schug B, Wedemeyer RS. Tellone V, et al. Among authors: del vecchio a. Int J Clin Pharmacol Ther. 2020 Jul 27. doi: 10.5414/CP203652. Online ahead of print. Int J Clin Pharmacol Ther. 2020. PMID: 32716291
Lung recruitment before surfactant administration in extremely preterm neonates with respiratory distress syndrome (IN-REC-SUR-E): a randomised, unblinded, controlled trial.
Vento G, Ventura ML, Pastorino R, van Kaam AH, Carnielli V, Cools F, Dani C, Mosca F, Polglase G, Tagliabue P, Boni L, Cota F, Tana M, Tirone C, Aurilia C, Lio A, Costa S, D'Andrea V, Lucente M, Nigro G, Giordano L, Roma V, Villani PE, Fusco FP, Fasolato V, Colnaghi MR, Matassa PG, Vendettuoli V, Poggi C, Del Vecchio A, Petrillo F, Betta P, Mattia C, Garani G, Solinas A, Gitto E, Salvo V, Gargano G, Balestri E, Sandri F, Mescoli G, Martinelli S, Ilardi L, Ciarmoli E, Di Fabio S, Maranella E, Grassia C, Ausanio G, Rossi V, Motta A, Tina LG, Maiolo K, Nobile S, Messner H, Staffler A, Ferrero F, Stasi I, Pieragostini L, Mondello I, Haass C, Consigli C, Vedovato S, Grison A, Maffei G, Presta G, Perniola R, Vitaliti M, Re MP, De Curtis M, Cardilli V, Lago P, Tormena F, Orfeo L, Gizzi C, Massenzi L, Gazzolo D, Strozzi MCM, Bottino R, Pontiggia F, Berardi A, Guidotti I, Cacace C, Meli V, Quartulli L, Scorrano A, Casati A, Grappone L, Pillow JJ. Vento G, et al. Among authors: del vecchio a. Lancet Respir Med. 2020 Jul 17:S2213-2600(20)30179-X. doi: 10.1016/S2213-2600(20)30179-X. Online ahead of print. Lancet Respir Med. 2020. PMID: 32687801
Comparison of the Effects of Photobiomodulation with Different Lasers on Orthodontic Movement and Reduction of the Treatment Time with Fixed Appliances in Novel Scientific Reports: A Systematic Review with Meta-Analysis.
Jedliński M, Romeo U, Del Vecchio A, Palaia G, Galluccio G. Jedliński M, et al. Among authors: del vecchio a. Photobiomodul Photomed Laser Surg. 2020 Jul 15. doi: 10.1089/photob.2019.4779. Online ahead of print. Photobiomodul Photomed Laser Surg. 2020. PMID: 32678697
Gamma Knife Radiosurgery for Trigeminal Neuralgia: Role of Trigeminal Length and Pontotrigeminal Angle on Target Definition and on Clinical Effects.
Barzaghi LR, Albano L, Scudieri C, Gigliotti CR, Nadin F, Del Vecchio A, Mortini P. Barzaghi LR, et al. Among authors: del vecchio a. World Neurosurg. 2020 Jun 26:S1878-8750(20)31415-7. doi: 10.1016/j.wneu.2020.06.147. Online ahead of print. World Neurosurg. 2020. PMID: 32599193
Reproducibility of muscle fibre conduction velocity during linearly increasing force contractions.
Casolo A, Nuccio S, Bazzucchi I, Felici F, Del Vecchio A. Casolo A, et al. Among authors: del vecchio a. J Electromyogr Kinesiol. 2020 Jun 10;53:102439. doi: 10.1016/j.jelekin.2020.102439. Online ahead of print. J Electromyogr Kinesiol. 2020. PMID: 32563844
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