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Immunotherapy with MVA-BN®-HER2 induces HER-2-specific Th1 immunity and alters the intratumoral balance of effector and regulatory T cells.
Mandl SJ, Rountree RB, Dalpozzo K, Do L, Lombardo JR, Schoonmaker PL, Dirmeier U, Steigerwald R, Giffon T, Laus R, Delcayre A. Mandl SJ, et al. Among authors: delcayre a. Cancer Immunol Immunother. 2012 Jan;61(1):19-29. doi: 10.1007/s00262-011-1077-4. Epub 2011 Aug 7. Cancer Immunol Immunother. 2012. PMID: 21822917 Free PMC article.
Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.
Foy SP, Mandl SJ, dela Cruz T, Cote JJ, Gordon EJ, Trent E, Delcayre A, Breitmeyer J, Franzusoff A, Rountree RB. Foy SP, et al. Among authors: delcayre a. Cancer Immunol Immunother. 2016 May;65(5):537-49. doi: 10.1007/s00262-016-1816-7. Epub 2016 Mar 10. Cancer Immunol Immunother. 2016. PMID: 26961085 Free PMC article.
Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation.
Wang JH, Forterre AV, Zhao J, Frimannsson DO, Delcayre A, Antes TJ, Efron B, Jeffrey SS, Pegram MD, Matin AC. Wang JH, et al. Among authors: delcayre a. Mol Cancer Ther. 2018 May;17(5):1133-1142. doi: 10.1158/1535-7163.MCT-17-0827. Epub 2018 Feb 26. Mol Cancer Ther. 2018. PMID: 29483213 Free PMC article.
Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy.
Mandl SJ, Rountree RB, Dela Cruz TB, Foy SP, Cote JJ, Gordon EJ, Trent E, Delcayre A, Franzusoff A. Mandl SJ, et al. Among authors: delcayre a. J Immunother Cancer. 2014 Oct 14;2(1):34. doi: 10.1186/s40425-014-0034-0. eCollection 2014. J Immunother Cancer. 2014. PMID: 25328681 Free PMC article.
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