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CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo.
Salzler R, DiLillo DJ, Saotome K, Bray K, Mohrs K, Hwang H, Cygan KJ, Shah D, Rye-Weller A, Kundu K, Badithe A, Zhang X, Garnova E, Torres M, Dhanik A, Babb R, Delfino FJ, Thwaites C, Dudgeon D, Moore MJ, Meagher TC, Decker CE, Owczarek T, Gleason JA, Yang X, Suh D, Lee WY, Welsh R, MacDonald D, Hansen J, Guo C, Kirshner JR, Thurston G, Huang T, Franklin MC, Yancopoulos GD, Lin JC, Macdonald LE, Murphy AJ, Chen G, Olsen O, Olson WC. Salzler R, et al. Among authors: delfino fj. Sci Transl Med. 2025 Mar 26;17(791):eado9371. doi: 10.1126/scitranslmed.ado9371. Epub 2025 Mar 26. Sci Transl Med. 2025. PMID: 40138458
[ARGEN-IAM-ST Registry: older adults with infarction: Are they all the same?].
Castillo Costa Y, Delfino F, Palacio S, Charask A, Mauro V, Macín S, Zapata G, D Imperio H, Thierer J, Gagliardi J; Grupo ARGEN IAM ST. Castillo Costa Y, et al. Among authors: delfino f. Medicina (B Aires). 2024;84(4):682-688. Medicina (B Aires). 2024. PMID: 39172568 Free article. Spanish.
Cardiogenic shock in the context of acute coronary syndromes in Latin America ("LATIN Shock").
Castillo Costa Y, Delfino F, Mauro V, D Imperio H, Adamowski M, Cortez Sandoval MA, Pow Chon Long F, Macín SM, Burgos Acosta J, Chacón-Díaz M, Soldán Patiño CP. Castillo Costa Y, et al. Among authors: delfino f. Curr Probl Cardiol. 2024 Oct;49(10):102745. doi: 10.1016/j.cpcardiol.2024.102745. Epub 2024 Aug 10. Curr Probl Cardiol. 2024. PMID: 39128226
Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain.
Somersan-Karakaya S, Turner KC, Cortes-Burgos L, Miller J, LaCroix-Fralish M, Logovinsky V, Patel Y, Torres R, Ganguly S, Breazna A, DeVeaux M, Bhore R, Gao M, Delfino FJ, Rafique A, Fairhurst JL, Hunt C, Babb R, Badithe A, Poueymirou WT, Surowitz R, Rottey S, Murphy AJ, Harari O, Macdonald LE, Croll SD. Somersan-Karakaya S, et al. Among authors: delfino fj. Neurobiol Pain. 2023 Jun 26;14:100136. doi: 10.1016/j.ynpai.2023.100136. eCollection 2023 Aug-Dec. Neurobiol Pain. 2023. PMID: 38099276 Free PMC article.
Clinical characteristics and evolution of patients with cardiogenic shock in Argentina in the context of an acute myocardial infarction with ST segment elevation. Data from the nationwide ARGEN-IAM-ST Registry.
Castillo Costa Y, Delfino F, Mauro V, D'Imperio H, Barrero C, Charask A, Zoni R, Macín S, Perna E, Gagliardi J. Castillo Costa Y, et al. Among authors: delfino f. Curr Probl Cardiol. 2023 Feb;48(2):101468. doi: 10.1016/j.cpcardiol.2022.101468. Epub 2022 Oct 17. Curr Probl Cardiol. 2023. PMID: 36261099 Review.
Allogeneic CD20-targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B-cell lymphoma models.
Nishimoto KP, Barca T, Azameera A, Makkouk A, Romero JM, Bai L, Brodey MM, Kennedy-Wilde J, Shao H, Papaioannou S, Doan A, Masri C, Hoang NT, Tessman H, Ramanathan VD, Giner-Rubio A, Delfino F, Sharma K, Bray K, Hoopes M, Satpayev D, Sengupta R, Herrman M, Abbot SE, Aftab BT, An Z, Panuganti S, Hayes SM. Nishimoto KP, et al. Among authors: delfino f. Clin Transl Immunology. 2022 Feb 2;11(2):e1373. doi: 10.1002/cti2.1373. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35136603 Free PMC article.
A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade.
DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, Delfino FJ, Mao S, Zhao F, Giurleo JT, Kelly MP, Makonnen S, Hickey C, Krueger P, Foster R, Chen Z, Retter MW, Slim R, Young TM, Olson WC, Thurston G, Daly C. DaSilva JO, et al. Among authors: delfino fj. Mol Cancer Ther. 2021 Oct;20(10):1966-1976. doi: 10.1158/1535-7163.MCT-21-0009. Epub 2021 Jul 26. Mol Cancer Ther. 2021. PMID: 34315762 Free PMC article.
45 results