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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1934 1
1940 2
1946 1
1947 1
1950 3
1951 1
1955 1
1956 2
1957 2
1958 4
1959 2
1960 4
1961 4
1962 9
1963 16
1964 18
1965 20
1966 35
1967 52
1968 39
1969 71
1970 61
1971 64
1972 105
1973 96
1974 145
1975 292
1976 311
1977 358
1978 418
1979 589
1980 612
1981 745
1982 845
1983 1088
1984 1311
1985 1538
1986 1777
1987 1973
1988 2414
1989 3044
1990 3446
1991 3819
1992 4399
1993 5033
1994 5761
1995 6308
1996 6683
1997 7194
1998 7487
1999 7835
2000 8390
2001 8328
2002 8268
2003 8549
2004 9244
2005 9636
2006 9975
2007 10462
2008 10787
2009 10616
2010 11314
2011 11846
2012 12504
2013 12719
2014 12725
2015 12727
2016 12648
2017 12377
2018 12532
2019 12694
2020 13187
2021 13606
2022 12995
2023 12207
2024 4255

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322,371 results

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Page 1
Showing results for delete a
Search for Delute A instead (1 results)
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.
Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H. Baba T, et al. Mol Syst Biol. 2006;2:2006.0008. doi: 10.1038/msb4100050. Epub 2006 Feb 21. Mol Syst Biol. 2006. PMID: 16738554 Free PMC article.
We have systematically made a set of precisely defined, single-gene deletions of all nonessential genes in Escherichia coli K-12. ...To alleviate problems encountered in high-throughput studies, two independent mutants were saved for every deleted gene …
We have systematically made a set of precisely defined, single-gene deletions of all nonessential genes in Escherichia coli K- …
Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis.
Koo BM, Kritikos G, Farelli JD, Todor H, Tong K, Kimsey H, Wapinski I, Galardini M, Cabal A, Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA. Koo BM, et al. Cell Syst. 2017 Mar 22;4(3):291-305.e7. doi: 10.1016/j.cels.2016.12.013. Epub 2017 Feb 8. Cell Syst. 2017. PMID: 28189581 Free PMC article.
To this end, we constructed two ordered, barcoded, erythromycin-resistance- and kanamycin-resistance-marked single-gene deletion libraries of the Gram-positive model organism, Bacillus subtilis. ...Finally, we describe a suite of high-throughput phenotyping methodol …
To this end, we constructed two ordered, barcoded, erythromycin-resistance- and kanamycin-resistance-marked single-gene deletion …
A copy number variation map of the human genome.
Zarrei M, MacDonald JR, Merico D, Scherer SW. Zarrei M, et al. Nat Rev Genet. 2015 Mar;16(3):172-83. doi: 10.1038/nrg3871. Epub 2015 Feb 3. Nat Rev Genet. 2015. PMID: 25645873 Review.
A major contribution to the genome variability among individuals comes from deletions and duplications - collectively termed copy number variations (CNVs) - which alter the diploid status of DNA. ...Depending on the level of stringency of the map, we estimated that 4.8-9.5 …
A major contribution to the genome variability among individuals comes from deletions and duplications - collectively termed copy num …
A theory that may explain the Hayflick limit--a means to delete one copy of a repeating sequence during each cell cycle in certain human cells such as fibroblasts.
Naveilhan P, Baudet C, Jabbour W, Wion D. Naveilhan P, et al. Mech Ageing Dev. 1994 Sep;75(3):205-13. doi: 10.1016/0047-6374(94)90010-8. Mech Ageing Dev. 1994. PMID: 7845054
The central postulate of this theory is that there exists, prior to certain key exons that code for materials needed for cell division, a unique sequence of specific repeating segments of DNA. One copy of such repeating segments is deleted during each cell cycle in …
The central postulate of this theory is that there exists, prior to certain key exons that code for materials needed for cell division, a un …
Allelic-Exchange Procedure in Staphylococcus aureus.
Zeden MS, Schuster CF, Gründling A. Zeden MS, et al. Cold Spring Harb Protoc. 2023 Aug 1;2023(8):107948. doi: 10.1101/pdb.prot107948. Cold Spring Harb Protoc. 2023. PMID: 37117017
This protocol continues a series of methods for the construction of an in-frame gene deletion in Staphylococcus aureus strain RN4220. To this end, we describe in this protocol an allelic-exchange procedure for S. aureus We have previously described how an allelic-ex …
This protocol continues a series of methods for the construction of an in-frame gene deletion in Staphylococcus aureus strain …
Implication of a gene deletion on a Salmonella Enteritidis phage growth parameters.
Milho C, Sillankorva S. Milho C, et al. Virus Res. 2022 Jan 15;308:198654. doi: 10.1016/j.virusres.2021.198654. Epub 2021 Dec 11. Virus Res. 2022. PMID: 34902446
In this work, Bacteriophage Recombineering of Electroporated DNA was used to assess the influence of deletion of a single gene with unknown function in the overall replication parameters of Salmonella phage PVP-SE2. ...A direct consequence of the deletion led …
In this work, Bacteriophage Recombineering of Electroporated DNA was used to assess the influence of deletion of a single gene …
Delete and repeat: a comprehensive toolkit for sequential gene knockout in the budding yeast Saccharomyces cerevisiae.
Hegemann JH, Heick SB. Hegemann JH, et al. Methods Mol Biol. 2011;765:189-206. doi: 10.1007/978-1-61779-197-0_12. Methods Mol Biol. 2011. PMID: 21815094
Gene inactivation is an essential step in the molecular dissection of gene function. In the yeast Saccharomyces cerevisiae, many tools for gene disruption are available. Gene disruption cassettes comprising completely heterologous marker genes flanked …
Gene inactivation is an essential step in the molecular dissection of gene function. In the yeast Saccharomyces cerevisiae, ma …
Genetic Manipulation of Haloferax Species.
Dattani A, Harrison C, Allers T. Dattani A, et al. Methods Mol Biol. 2022;2522:33-56. doi: 10.1007/978-1-0716-2445-6_3. Methods Mol Biol. 2022. PMID: 36125742
In this chapter, we describe the reverse genetics methodology behind generating a targeted gene deletion or replacement in archaeal species of the genus Haloferax, which are renowned for their ease of manipulation. ...The vector carries DNA fragments of 500-1000 bp …
In this chapter, we describe the reverse genetics methodology behind generating a targeted gene deletion or replacement in arc …
A markerless protocol for genetic analysis of Aggregatibacter actinomycetemcomitans.
Cheng YA, Jee J, Hsu G, Huang Y, Chen C, Lin CP. Cheng YA, et al. J Formos Med Assoc. 2014 Feb;113(2):114-23. doi: 10.1016/j.jfma.2012.05.005. Epub 2012 Aug 11. J Formos Med Assoc. 2014. PMID: 24530245 Free PMC article.
Genetic analysis for the functions of these islands will be constrained by the limited availability of genetic markers and vectors for A actinomycetemcomitans. In this study, we tested a novel genetic approach of gene deletion and restoration in a naturally competen …
Genetic analysis for the functions of these islands will be constrained by the limited availability of genetic markers and vectors for A act …
322,371 results
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