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154 results
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A phase I study of the combination of sorafenib with temozolomide and radiation therapy for the treatment of primary and recurrent high-grade gliomas.
Den RB, Kamrava M, Sheng Z, Werner-Wasik M, Dougherty E, Marinucchi M, Lawrence YR, Hegarty S, Hyslop T, Andrews DW, Glass J, Friedman DP, Green MR, Camphausen K, Dicker AP. Den RB, et al. Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):321-8. doi: 10.1016/j.ijrobp.2012.04.017. Epub 2012 Jun 9. Int J Radiat Oncol Biol Phys. 2013. PMID: 22687197 Free PMC article. Clinical Trial.
A hormone-DNA repair circuit governs the response to genotoxic insult.
Goodwin JF, Schiewer MJ, Dean JL, Schrecengost RS, de Leeuw R, Han S, Ma T, Den RB, Dicker AP, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: den rb. Cancer Discov. 2013 Nov;3(11):1254-71. doi: 10.1158/2159-8290.CD-13-0108. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027197 Free PMC article.
AR function in promoting metastatic prostate cancer.
Augello MA, Den RB, Knudsen KE. Augello MA, et al. Among authors: den rb. Cancer Metastasis Rev. 2014 Sep;33(2-3):399-411. doi: 10.1007/s10555-013-9471-3. Cancer Metastasis Rev. 2014. PMID: 24425228 Free PMC article. Review.
The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness.
Thangavel C, Boopathi E, Ciment S, Liu Y, O'Neill R, Sharma A, McMahon SB, Mellert H, Addya S, Ertel A, Birbe R, Fortina P, Dicker AP, Knudsen KE, Den RB. Thangavel C, et al. Among authors: den rb. Clin Cancer Res. 2014 Nov 1;20(21):5468-5482. doi: 10.1158/1078-0432.CCR-14-0326. Epub 2014 Aug 27. Clin Cancer Res. 2014. PMID: 25165096 Free PMC article.
Novel actions of next-generation taxanes benefit advanced stages of prostate cancer.
de Leeuw R, Berman-Booty LD, Schiewer MJ, Ciment SJ, Den RB, Dicker AP, Kelly WK, Trabulsi EJ, Lallas CD, Gomella LG, Knudsen KE. de Leeuw R, et al. Among authors: den rb. Clin Cancer Res. 2015 Feb 15;21(4):795-807. doi: 10.1158/1078-0432.CCR-14-1358. Clin Cancer Res. 2015. PMID: 25691773 Free PMC article.
High-throughput transcriptomic analysis nominates proteasomal genes as age-specific biomarkers and therapeutic targets in prostate cancer.
Zhao SG, Jackson WC, Kothari V, Schipper MJ, Erho N, Evans JR, Speers C, Hamstra DA, Niknafs YS, Nguyen PL, Schaeffer EM, Ross AE, Den RB, Klein EA, Jenkins RB, Davicioni E, Feng FY. Zhao SG, et al. Among authors: den rb. Prostate Cancer Prostatic Dis. 2015 Sep;18(3):229-36. doi: 10.1038/pcan.2015.22. Epub 2015 May 19. Prostate Cancer Prostatic Dis. 2015. PMID: 25986914 Free PMC article.
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.
Goodwin JF, Kothari V, Drake JM, Zhao S, Dylgjeri E, Dean JL, Schiewer MJ, McNair C, Jones JK, Aytes A, Magee MS, Snook AE, Zhu Z, Den RB, Birbe RC, Gomella LG, Graham NA, Vashisht AA, Wohlschlegel JA, Graeber TG, Karnes RJ, Takhar M, Davicioni E, Tomlins SA, Abate-Shen C, Sharifi N, Witte ON, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: den rb. Cancer Cell. 2015 Jul 13;28(1):97-113. doi: 10.1016/j.ccell.2015.06.004. Cancer Cell. 2015. PMID: 26175416 Free PMC article.
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